lactide
lactide structure
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Common Name | lactide | ||
|---|---|---|---|---|
| CAS Number | 95-96-5 | Molecular Weight | 144.125 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 285.5±15.0 °C at 760 mmHg | |
| Molecular Formula | C6H8O4 | Melting Point | 116-119ºC | |
| MSDS | USA | Flash Point | 150.6±18.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Magnesium amino-bis(phenolato) complexes for the ring-opening polymerization of rac-lactide.
Dalton Trans. 44 , 12365-75, (2015) Magnesium compounds of tetradentate amino-bis(phenolato) ligands, Mg[L1] (1) and Mg[L2] (2) (where [L1] = 2-pyridyl-N,N-bis(2-methylene-4-methoxy-6-tert-butylphenolato), and [L2] = dimethylaminoethylamino-N,N-bis(2-methylene-4-methyl-6-tert-butylphenolato)) w... |
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The influence of spray-drying parameters on phase behavior, drug distribution, and in vitro release of injectable microspheres for sustained release.
J. Pharm. Sci. 104(4) , 1451-60, (2015) For ternary solid dispersions, it is indispensable to characterize their structure, phase behavior, and the spatial distribution of the dispersed drug as this might influence the release profile and/or stability of these formulations. This study shows how for... |
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Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell-Nanoparticle Interaction.
ACS Nano 9 , 9912-21, (2015) The functionalized lipid shell of hybrid nanoparticles plays an important role for improving their biocompatibility and in vivo stability. Yet few efforts have been made to critically examine the shell structure of nanoparticles and its effect on cell-particl... |
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Development and optimization of N-Acetylcysteine-loaded poly (lactic-co-glycolic acid) nanoparticles by electrospray.
Int. J. Biol. Macromol. 72 , 764-70, (2014) N-Acetylcysteine (NAC) loaded PLGA nanoparticles were prepared by electrospray method. The influence of independent parameters such as concentration, flow rate and nozzle to collector distance was studied on particle size and size distribution of generated na... |
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Controlling microencapsulation and release of micronized proteins using poly(ethylene glycol) and electrospraying.
Eur. J. Pharm. Biopharm. 87(2) , 366-77, (2014) The fabrication of tailored microparticles for delivery of therapeutics is a challenge relying upon a complex interplay between processing parameters and materials properties. The emerging use of electrospraying allows better tailoring of particle morphologie... |
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Exendin-4-loaded PLGA microspheres relieve cerebral ischemia/reperfusion injury and neurologic deficits through long-lasting bioactivity-mediated phosphorylated Akt/eNOS signaling in rats.
J. Cereb. Blood Flow Metab. 35 , 1790-803, (2015) Glucagon-like peptide-1 (GLP-1) receptor activation in the brain provides neuroprotection. Exendin-4 (Ex-4), a GLP-1 analog, has seen limited clinical usage because of its short half-life. We developed long-lasting Ex-4-loaded poly(D,L-lactide-co-glycolide) m... |
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3D imaging of cell interactions with electrospun PLGA nanofiber membranes for bone regeneration.
Acta Biomater. 27 , 88-100, (2015) The interaction between resident cells and electrospun nanofibers is critical in determining resultant osteoblast proliferation and activity in orthopedic tissue scaffolds. The use of techniques to evaluate cell-nanofiber interactions is critical in understan... |
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Bio-inspired oligovitronectin-grafted surface for enhanced self-renewal and long-term maintenance of human pluripotent stem cells under feeder-free conditions.
Biomaterials 50 , 127-39, (2015) Current protocols for human pluripotent stem cell (hPSC) expansion require feeder cells or matrices from animal sources that have been the major obstacle to obtain clinical grade hPSCs due to safety issues, difficulty in quality control, and high expense. Thu... |
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Comparison of osteogenic differentiation potential of human adult stem cells loaded on bioceramic-coated electrospun poly (L-lactide) nanofibres.
Cell Prolif. 48(1) , 47-58, (2015) To compare potential of four types of stem cell in tissue engineering and regenerative medicine applications, osteogenic capacity of newly introduced mesenchymal stem cells (MSCs) derived from buccal fat pads (BFP) (an adipose-encapsulated mass of the oral ca... |
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Bioactive Hybrid Particles from Poly(D,L-lactide-co-glycolide) Nanoparticle Stabilized Lipid Droplets.
ACS Appl. Mater. Interfaces 7 , 17460-70, (2015) Biodegradable and bioactive hybrid particles composed of poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles and medium-chain triglycerides were prepared by spray drying lipid-in-water emulsions stabilized by PLGA nanoparticles, to form PLGA-lipid hybrid (PLH... |