lactide

Modify Date: 2024-01-03 19:08:25

lactide Structure
lactide structure
Common Name lactide
CAS Number 95-96-5 Molecular Weight 144.125
Density 1.2±0.1 g/cm3 Boiling Point 285.5±15.0 °C at 760 mmHg
Molecular Formula C6H8O4 Melting Point 116-119ºC
MSDS USA Flash Point 150.6±18.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 3,6-Dimethyl-1,4-dioxane-2,5-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 285.5±15.0 °C at 760 mmHg
Melting Point 116-119ºC
Molecular Formula C6H8O4
Molecular Weight 144.125
Flash Point 150.6±18.8 °C
Exact Mass 144.042252
PSA 52.60000
LogP -1.45
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.429
Storage condition 2~8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JH1100000
CHEMICAL NAME :
1,4-Dioxane-2,5-dione, 3,6-dimethyl-
CAS REGISTRY NUMBER :
95-96-5
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H8-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
35 gm/kg/2W-I
TOXIC EFFECTS :
Gastrointestinal - changes in structure or function of esophagus Gastrointestinal - ulceration or bleeding from stomach Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 36(1, Pt 2),274,1997
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
9100 mg/kg/13W-I
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 36(1, Pt 2),274,1997

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3.0
RTECS JH1100000
HS Code 2934999090

 Synthetic Route

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles82

More Articles
Magnesium amino-bis(phenolato) complexes for the ring-opening polymerization of rac-lactide.

Dalton Trans. 44 , 12365-75, (2015)

Magnesium compounds of tetradentate amino-bis(phenolato) ligands, Mg[L1] (1) and Mg[L2] (2) (where [L1] = 2-pyridyl-N,N-bis(2-methylene-4-methoxy-6-tert-butylphenolato), and [L2] = dimethylaminoethyla...

The influence of spray-drying parameters on phase behavior, drug distribution, and in vitro release of injectable microspheres for sustained release.

J. Pharm. Sci. 104(4) , 1451-60, (2015)

For ternary solid dispersions, it is indispensable to characterize their structure, phase behavior, and the spatial distribution of the dispersed drug as this might influence the release profile and/o...

Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell-Nanoparticle Interaction.

ACS Nano 9 , 9912-21, (2015)

The functionalized lipid shell of hybrid nanoparticles plays an important role for improving their biocompatibility and in vivo stability. Yet few efforts have been made to critically examine the shel...

 Synonyms

L-(-)-Dilactide
(3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione
L-(-)-Lactide
3,6-Dimethyl-1,4-dioxane-2,5-dione
1,4-Dioxane-2,5-dione, 3,6-dimethyl-
EINECS 202-468-3
UNII:7EH08MWO6M
L-Lactide
MFCD00011685
DL-Lactide
lactide
(3S,6S)-(-)-3,6-Dimethyl-1,4-dioxane-2,5-dione
Propanoic acid, 2-hydroxy-, bimol. cyclic ester
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