9-AMINO-6-CHLORO-2-METHOXYACRIDINE
9-AMINO-6-CHLORO-2-METHOXYACRIDINE structure
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Common Name | 9-AMINO-6-CHLORO-2-METHOXYACRIDINE | ||
|---|---|---|---|---|
| CAS Number | 3548-09-2 | Molecular Weight | 258.70300 | |
| Density | 1.367g/cm3 | Boiling Point | 475.1ºC at 760mmHg | |
| Molecular Formula | C14H11ClN2O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 241.2ºC | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
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Vma9p need not be associated with the yeast V-ATPase for fully-coupled proton pumping activity in vitro.
Biochemistry 54(3) , 853-8, (2015) Vacuolar-type ATPases (V-ATPases) acidify numerous intracellular compartments in all eukaryotic cells and are responsible for extracellular acidification in some specialized cells. V-ATPases are large macromolecular complexes with at least 15 different subuni... |
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Adaptation by the collecting duct to an exogenous acid load is blunted by deletion of the proton-sensing receptor GPR4.
Am. J. Physiol. Renal Physiol. 309 , F120-36, (2015) We previously reported that the deletion of the pH sensor GPR4 causes a non-gap metabolic acidosis and defective net acid excretion (NAE) in the GPR4 knockout mouse (GPR4-/-) (Sun X, Yang LV, Tiegs BC, Arend LJ, McGraw DW, Penn RB, and Petrovic S. J Am Soc Ne... |
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Copper transport and compartmentation in grape cells.
Plant Cell Physiol. 53(11) , 1866-80, (2012) Copper-based fungicides have been widely used against several grapevine (Vitis vinifera L.) diseases since the late 1800s when the Bordeaux mixture was developed, but their intensive use has raised phytotoxicity concerns. In this study, physiological, biochem... |
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Constraining the Lateral Helix of Respiratory Complex I by Cross-linking Does Not Impair Enzyme Activity or Proton Translocation.
J. Biol. Chem. 290 , 20761-73, (2015) Complex I (NADH:ubiquinone oxidoreductase) is a multisubunit, membrane-bound enzyme of the respiratory chain. The energy from NADH oxidation in the peripheral region of the enzyme is used to drive proton translocation across the membrane. One of the integral ... |
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Mitochondrial ATPase activity and membrane fluidity changes in rat liver in response to intoxication with buckthorn (Karwinskia humboldtiana).
Biol. Res. 48 , 17, (2015) Karwinskia humboldtiana (Kh) is a poisonous plant of the rhamnacea family. To elucidate some of the subcellular effects of Kh toxicity, membrane fluidity and ATPase activities as hydrolytic and as proton-pumping activity were assessed in rat liver submitochon... |
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Mimicking respiratory phosphorylation using purified enzymes.
Biochim. Biophys. Acta 1857 , 321-31, (2016) The enzymes of oxidative phosphorylation is a striking example of the functional association of multiple enzyme complexes, working together to form ATP from cellular reducing equivalents. These complexes, such as cytochrome c oxidase or the ATP synthase, are ... |
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Apoptosis-inducing Factor (AIF) and Its Family Member Protein, AMID, Are Rotenone-sensitive NADH:Ubiquinone Oxidoreductases (NDH-2).
J. Biol. Chem. 290 , 20815-26, (2015) Apoptosis-inducing factor (AIF) and AMID (AIF-homologous mitochondrion-associated inducer of death) are flavoproteins. Although AIF was originally discovered as a caspase-independent cell death effector, bioenergetic roles of AIF, particularly relating to com... |
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Conserved amino acid residues of the NuoD segment important for structure and function of Escherichia coli NDH-1 (complex I).
Biochemistry 54(3) , 753-64, (2015) The NuoD segment (homologue of mitochondrial 49 kDa subunit) of the proton-translocating NADH:quinone oxidoreductase (complex I/NDH-1) from Escherichia coli is in the hydrophilic domain and bears many highly conserved amino acid residues. The three-dimensiona... |
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Physiological ligands ADP and Pi modulate the degree of intrinsic coupling in the ATP synthase of the photosynthetic bacterium Rhodobacter capsulatus.
Biochemistry 43(34) , 11126-34, (2004) The proton-pumping and the ATP hydrolysis activities of the ATP synthase of Rhodobacter capsulatus have been compared as a function of the ADP and P(i) concentrations. The proton pumping was measured either with the transmembrane pH difference probe, 9-amino-... |
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Distance-dependent activation energies for hole injection from protonated 9-amino-6-chloro-2-methoxyacridine into duplex DNA.
J. Am. Chem. Soc. 124(11) , 2422-3, (2002) The recent investigation of the apparently anomalous attenuation factor (beta > 1.5 A(-1)) for photoinduced hole injection into DNA duplexes modified by protonated 9-amino-6-chloro-2-methoxyacridine (X+) led to the conclusion that in addition to the electroni... |