2,3-Diaminophenazine
2,3-Diaminophenazine structure
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Common Name | 2,3-Diaminophenazine | ||
|---|---|---|---|---|
| CAS Number | 655-86-7 | Molecular Weight | 210.235 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 497.8±15.0 °C at 760 mmHg | |
| Molecular Formula | C12H10N4 | Melting Point | >300ºC | |
| MSDS | Chinese USA | Flash Point | 287.1±7.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Spectrophotometric quantification of horseradish peroxidase with o-phenylenediamine.
Anal. Biochem. 407(2) , 293-5, (2010) The assay conditions for the spectrophotometric quantification of horseradish peroxidase (HRP) with the chromogenic substrate o-phenylenediamine (OPD) at 25°C in the presence of hydrogen peroxide (H(2)O(2)) were optimized. With [OPD](0)=3.14 mM and [H(2)O(2)]... |
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Spectrophotometric quantification of lactose in solution with a peroxidase-based enzymatic cascade reaction system.
Anal. Bioanal. Chem 401 , 2307-2310, (2011) A spectrophotometric assay was developed for the quantification of lactose in aqueous solution via a one-pot enzymatic cascade reaction at 25 °C and pH 7.2. Lactose (0.2-1.8 mM), E. coli β-galactosidase (β-Gal), Aspergillus niger glucose oxidase (GOD), horser... |
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Photoinduced DNA cleavage and cellular damage in human dermal fibroblasts by 2,3-diaminophenazine.
Photochem. Photobiol. 81(1) , 89-95, (2005) Aromatic amines, such as o-phenylenediamine (OPD), have been used extensively in commercial hair dyes and in the synthesis of agricultural pesticides. Air oxidation of OPD results in the formation of 2,3-diaminophenazine (DAP). Although the mutagenic toxicity... |
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Experimental (FT-IR, FT-Raman and UV-Vis) spectra and theoretical DFT investigations of 2,3-diaminophenazine.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 96 , 401-12, (2012) Vibrational analysis of the planar electron-rich heterocyclic 2,3-diaminophenazine (DAP) molecule was carried out using FT-IR and FT-Raman spectroscopic techniques. The equilibrium geometry, harmonic vibrational wavenumbers, various bonding features have been... |
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Studies on the genotoxic effects of aminophenazines using two cellular models and three different methods.
Mutat. Res. 446(1) , 57-65, (1999) This paper presents studies on the genotoxicity of two aminophenazines: 2,3-diaminophenazine (DAP) and 2-amino-3-hydroxyphenazine (AHP). The genotoxic activities of these compounds were evaluated with human lymphocytes using the alkaline single cell gel elect... |
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[The study on reaction kinetics based on a new system of the horseradish peroxidase catalyting the oxidation of o-phenylenediamine by H2O2].
Guang Pu Xue Yu Guang Pu Fen Xi 22(3) , 436-40, (2002) In this paper, we study the enzyme catalysis reaction kinetics that 2,3-diaminophenazine compound was synthesized with the horseradish peroxidase catalyzing reaction of H2O2 oxidizing o-phenylemediamine. First, the product of oxidation of o-phenylenediamine (... |
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Identification of intermediate and product from methemoglobin-catalyzed oxidation of o-phenylenediamine in two-phase aqueous-organic system.
Biochemistry. (Mosc.) 70(1) , 92-9, (2005) Methemoglobin (metHb) was used as a mimetic enzyme for peroxidase to catalyze the oxidation reaction of o-phenylenediamine (OPDA) with H2O2 functioning as an oxidant. A reaction intermediate was obtained in two-phase aqueous-organic system and an absorption p... |
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2,3-Diaminophenazine is the product from the horseradish peroxidase-catalyzed oxidation of o-phenylenediamine.
Anal. Biochem. 165 , 230, (1987) NMR and mass spectroscopic evidence has been obtained which indicates that the product of the oxidation of o-phenylenediamine by hydrogen peroxide, uncatalyzed or catalyzed by horseradish peroxidase, is 2,3-diaminophenazine. These results settle disparate lit... |
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Development of an enzymatic microreactor based on microencapsulated laccase with off-line capillary electrophoresis for measurement of oxidation reactions.
J. Chromatogr. A. 1216(47) , 8270-6, (2009) Microencapsulation is used here as a new technique to immobilize enzymes in a microreactor coupled off-line to capillary electrophoresis (CE), allowing the determination of enzymatic reaction products. The redox enzyme laccase was encapsulated using the metho... |
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Effects of advanced glycation end-product inhibition and cross-link breakage in diabetic rats.
Metab. Clin. Exp. 49(8) , 996-1000, (2000) The accelerated formation of advanced glycation end-products (AGEs) due to elevated glycemia has repeatedly been reported as a central pathogenic factor in the development of diabetic microvascular complications. The effects of a novel inhibitor of AGE format... |