Methyl vinyl ketone
Methyl vinyl ketone structure
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Common Name | Methyl vinyl ketone | ||
|---|---|---|---|---|
| CAS Number | 78-94-4 | Molecular Weight | 70.090 | |
| Density | 0.8±0.1 g/cm3 | Boiling Point | 81.4±0.0 °C at 760 mmHg | |
| Molecular Formula | C4H6O | Melting Point | -7°C | |
| MSDS | Chinese USA | Flash Point | -6.7±0.0 °C | |
| Symbol |
GHS02, GHS05, GHS06, GHS09 |
Signal Word | Danger | |
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Modulation of mitochondrial glutathione status and cellular energetics in primary cultures of proximal tubular cells from remnant kidney of uninephrectomized rats.
Biochem. Pharmacol. 85(9) , 1379-88, (2013) Compensatory renal hypertrophy following reduction in renal mass leads to a hypermetabolic state and increases in basal mitochondrial oxidative stress and susceptibility to several nephrotoxicants. Previous studies provide conflicting data on whether renal mi... |
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Methyl vinyl ketone, a toxic ingredient in cigarette smoke extract, modifies glutathione in mouse melanoma cells.
Chem. Pharm. Bull. 62(8) , 772-8, (2014) Cigarette smoke contains many harmful chemicals, which contribute to the pathogenesis of smoking-related diseases such as chronic obstructive pulmonary disease, cancer and cardiovascular disease. The cytotoxicity of cigarette smoke is well documented, but the... |
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Quantum mechanical/molecular mechanical modeling finds Diels-Alder reactions are accelerated less on the surface of water than in water.
J. Am. Chem. Soc. 132(9) , 3097-104, (2010) Quantum and molecular mechanics calculations for the Diels-Alder reactions of cyclopentadiene with 1,4-naphthoquinone, methyl vinyl ketone, and acrylonitrile have been carried out at the vacuum-water interface and in the gas phase. In conjunction with previou... |
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Enantioselective Michael addition of 3-aryl-substituted oxindoles to methyl vinyl ketone catalyzed by a binaphthyl-modified bifunctional organocatalyst.
Molecules 17(6) , 7523-32, (2012) The enantioselective conjugate addition reaction of 3-aryl-substituted oxindoles with methyl vinyl ketone promoted by binaphthyl-modified bifunctional organocatalysts was investigated. The corresponding Michael adducts, containing a quaternary center at the C... |
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Diabetes increases susceptibility of primary cultures of rat proximal tubular cells to chemically induced injury.
Toxicol. Appl. Pharmacol. 241(1) , 1-13, (2009) Diabetic nephropathy is characterized by increased oxidative stress and mitochondrial dysfunction. In the present study, we prepared primary cultures of proximal tubular (PT) cells from diabetic rats 30 days after an ip injection of streptozotocin and compare... |
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Vinyl ketone reduction by three distinct Gluconobacter oxydans 621H enzymes.
Appl. Microbiol. Biotechnol. 80(6) , 995-1006, (2008) Three cytosolic NADPH-dependent flavin-associated proteins (Gox2107, Gox0502, and Gox2684) from Gluconobacter oxydans 621H were overproduced in Escherichia coli, and the recombinant enzymes were purified and characterized. Apparent native molecular masses of ... |
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Thermotolerant cyclamen with reduced acrolein and methyl vinyl ketone.
J. Exp. Bot. 63(11) , 4143-50, (2012) Reduced levels of trienoic fatty acids (TAs) in chloroplast membranes induce thermotolerance in several plant species, but the underlying mechanisms remain unclear. TA peroxidation in plant cell membranes generates cytotoxic, TA-derived compounds containing α... |
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Uptake of methacrolein and methyl vinyl ketone by tree saplings and implications for forest atmosphere.
Environ. Sci. Technol. 44(18) , 7096-101, (2010) Methacrolein (MACR) and methyl vinyl ketone (MVK) are oxygenates produced from isoprene which is abundantly emitted by trees. The uptake rate of these compounds by leaves of three different Quercus species, Q. acutissima, Q. myrsinaefolia, and Q. phillyraeoid... |
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Stereoselectivity in Diels-Alder reactions of diene-substituted N-alkoxycarbonyl-1,2-dihydropyridines.
J. Org. Chem. 72(9) , 3458-66, (2007) Diene substituent effects on the regiochemical and stereochemical outcomes of uncatalyzed Diels-Alder reactions of N-alkoxycarbonyl-1,2-dihydropyridines with both styrene and methyl vinyl ketone (MVK) were studied. Alkyl substitution on the diene in all cases... |
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Michael addition/pericyclization/rearrangement--a multicomponent strategy for the synthesis of substituted resorcinols.
Org. Biomol. Chem. 10(31) , 6388-94, (2012) The combination of methyl 3,7-dioxo-2-diazo-4-octenoate from the zinc triflate catalyzed Mukaiyama-Michael reaction of methyl 3-tert-butylsilyloxy-2-diazobutenoate and 4-methoxy-3-buten-2-one with Michael acceptors (methyl vinyl ketone, N-phenylmaleimide, β-n... |