AFLATOXIN M1

AFLATOXIN M1 Structure
AFLATOXIN M1 structure
Common Name AFLATOXIN M1
CAS Number 6795-23-9 Molecular Weight 328.273
Density 1.7±0.1 g/cm3 Boiling Point 644.3±55.0 °C at 760 mmHg
Molecular Formula C17H12O7 Melting Point 299℃
MSDS Chinese USA Flash Point 246.1±25.0 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Highly sensitive and simultaneous detection of melamine and aflatoxin M1 in milk products by multiplexed planar waveguide fluorescence immunosensor (MPWFI).

Food Chem. 197 , 359-66, (2015)

Mycotoxins and industrial chemicals, such as aflatoxin M1 and melamine, now commonly exist in milk and cause potential health risks. This study presents an indirect competitive immunoassay through multiplex planar waveguide fluorescence immunosensor (MPWFI) f...

Carry-over of aflatoxin B1 to aflatoxin M1 in high yielding Israeli cows in mid- and late-lactation.

Toxins (Basel.) 5(1) , 173-83, (2013)

The potent hepatotoxin and carcinogen aflatoxin B1 (AFB1) is a common mycotoxin contaminant of grains used in animal feeds. Aflatoxin M1 (AFM1) is the major metabolite of AFB1 in mammals, being partially excreted into milk, and is a possible human carcinogen....

Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2.

Toxicon 59(6) , 644-50, (2012)

Aflatoxins are natural contaminants frequently found both in food and feed. Many of them exert immunomodulatory properties in mammals; therefore, the aim of the current study was to investigate immune-effects of AFB1, AFB2, AFM1 and AFM2, alone and differentl...

Label-free detection of aflatoxin M1 with electrochemical Fe3O4/polyaniline-based aptasensor.

Mater. Sci. Eng. C. Mater. Biol. Appl. 33(4) , 2229-34, (2013)

The selective detection of ultratrace amounts of aflatoxin M1 (AFM1) is extremely important for food safety since it is the most toxic mycotoxin class that is allowed to be present on cow milk with strictly low regulatory levels. In this work, Fe3O4 incorpora...

Incidence of aflatoxin M1 in human and animal milk in Jordan.

J. Toxicol. Environ. Health A 75(22-23) , 1404-9, (2012)

This study was undertaken to determine the presence of aflatoxin M1 (AFM1) in animal milk. In addition, exposure of infants to aflatoxin M1 (AFM1) and lactating mothers to aflatoxin B1 (AFB1) was examined using AFM1 in breast milk as a biomarker for exposure ...

Occurrence of aflatoxin M1 in raw milk collected from traditional dairies in Morocco.

Food Chem. Toxicol. 50(8) , 2819-21, (2012)

A survey of the presence of aflatoxin M1 (AFM1) was carried out on eight traditional dairies belonging to four sectors of Fez city situated in the northern center of Morocco. Raw milk samples were collected between October 2009 and September 2010, and analyze...

Short communication: Occurrence of aflatoxin M1 in the Manchego cheese supply chain

J. Dairy Sci. 94(6) , 2775-8, (2011)

The importance of ewe milk lies in the production of high quality cheeses, such as Manchego cheese with a Protected Designation of Origin, whose safety must be guaranteed. In a 2-yr study, 407 bulk tank milk samples from farms and 82 silo milk and curd sample...

Testing the suitability of different high-performance liquid chromatographic methods to determine aflatoxin M1 in a soft fresh Italian cheese.

J. Chromatogr. A. 1218(29) , 4738-45, (2011)

Aflatoxin M1 (AFM1) is a toxic undesirable compound in milk. AFM1 affinity for caseins causes a concentration effect during milk process for dairy transformation. In spite of this, no official method of analysis, nor maximum tolerance level for aflatoxin M1 i...

Effect of adding a mycotoxin-sequestering agent on milk aflatoxin M₁ concentration and the performance and immune response of dairy cattle fed an aflatoxin B₁-contaminated diet.

J. Dairy Sci. 95(10) , 5901-8, (2012)

This project aimed to examine the effects of adding 2 doses of a montmorillonite-based mycotoxin adsorbent on milk aflatoxin M(1) (AFM(1)) concentrations and the performance and innate immune response of dairy cows fed an aflatoxin B(1) (AFB(1))-contaminated ...

Aflatoxin M1 determination in yoghurt produced in Guilan province of Iran using immunoaffinity column and high-performance liquid chromatography.

Toxicol. Ind. Health 29(1) , 72-6, (2013)

The present study was aimed to determine the presence and levels of aflatoxin M(1) (AFM(1)) in 120 natural yoghurt samples consisting of 80 samples of commercial and 40 samples of traditional yoghurt in Guilan province in the north of Iran. The occurrence and...