10-Deacetylbaccatin III
10-Deacetylbaccatin III structure
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Common Name | 10-Deacetylbaccatin III | ||
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| CAS Number | 32981-86-5 | Molecular Weight | 544.590 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 716.8±60.0 °C at 760 mmHg | |
| Molecular Formula | C29H36O10 | Melting Point | 231-236 °C | |
| MSDS | Chinese USA | Flash Point | 233.5±26.4 °C | |
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Disposition of [G-(3)H]paclitaxel and cremophor EL in a patient with severely impaired renal function.
Drug Metab. Dispos. 27 , 1300, (1999) In the present work, we studied the pharmacokinetics and metabolic disposition of [G-(3)H]paclitaxel in a female patient with recurrent ovarian cancer and severe renal impairment (creatinine clearance: approximately 20 ml/min) due to chronic hypertension and ... |
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Molecular mechanisms of patupilone resistance.
Cancer Res. 68 , 10197-10204, (2008) Patupilone is an epothilone in advanced clinical development that has shown promising efficacy in heavily pretreated patients. This study aimed at characterizing the mechanisms of patupilone activity in resistant patients. To this end, we generated patupilone... |
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Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli Kevin Walker and Rodney Croteau PNAS
Proc. 10th Am. Peptide Symp 97 , 13591-13596, (2000)
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Denis, J-N., et al.
J. Am. Chem. Soc. 110 , 5917, (1988)
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