10-脱乙酰基巴卡丁 III； 10-去乙酰基巴卡亭
10-脱乙酰基巴卡丁 III； 10-去乙酰基巴卡亭结构式
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常用名 | 10-脱乙酰基巴卡丁 III； 10-去乙酰基巴卡亭 | 英文名 | 10-Deacetylbaccatin III |
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| CAS号 | 32981-86-5 | 分子量 | 544.590 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 716.8±60.0 °C at 760 mmHg | |
| 分子式 | C29H36O10 | 熔点 | 231-236 °C | |
| MSDS | 中文版 美版 | 闪点 | 233.5±26.4 °C |
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Disposition of [G-(3)H]paclitaxel and cremophor EL in a patient with severely impaired renal function.
Drug Metab. Dispos. 27 , 1300, (1999) In the present work, we studied the pharmacokinetics and metabolic disposition of [G-(3)H]paclitaxel in a female patient with recurrent ovarian cancer and severe renal impairment (creatinine clearance: approximately 20 ml/min) due to chronic hypertension and ... |
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Molecular mechanisms of patupilone resistance.
Cancer Res. 68 , 10197-10204, (2008) Patupilone is an epothilone in advanced clinical development that has shown promising efficacy in heavily pretreated patients. This study aimed at characterizing the mechanisms of patupilone activity in resistant patients. To this end, we generated patupilone... |
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Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli Kevin Walker and Rodney Croteau PNAS
Proc. 10th Am. Peptide Symp 97 , 13591-13596, (2000)
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Denis, J-N., et al.
J. Am. Chem. Soc. 110 , 5917, (1988)
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