Fraxin

Fraxin Structure
Fraxin structure
Common Name Fraxin
CAS Number 524-30-1 Molecular Weight 370.308
Density 1.6±0.1 g/cm3 Boiling Point 722.2±60.0 °C at 760 mmHg
Molecular Formula C16H18O10 Melting Point 205-208ºC
MSDS Chinese USA Flash Point 267.1±26.4 °C

Screening for novel quorum-sensing inhibitors to interfere with the formation of Pseudomonas aeruginosa biofilm.

J. Med. Microbiol. 60(Pt 12) , 1827-34, (2011)

The objective of this study was to screen for novel quorum-sensing inhibitors (QSIs) from traditional Chinese medicines (TCMs) that inhibit bacterial biofilm formation. Six of 46 active components found in TCMs were identified as putative QSIs based on molecu...

[Studies on chemical constituents from stem barks of Fraxinus paxiana].

Zhongguo Zhong Yao Za Zhi 33(16) , 1990-3, (2008)

To investigate the chemical constituents of Fraxinus paxiana.The chemical constituents were isolated and purified by chromatographic techniques and the structures of the compounds were identified with or by spectroscopic methods.Fifteen compounds were obtaine...

[Coumarins from branch of Fraxinus sieboldiana and their antioxidative activity].

Zhongguo Zhong Yao Za Zhi 33(14) , 1708-10, (2008)

To investigate the chemical constituents from the branch of Fraxinus sieboldiana, and evaluate their antioxidative activity.The chemical constituents were isolated and purified by chromatographic techniques over silica gel, macroporous adsorbent resin, Sephad...

HIV gp41 binding phenolic components from Fraxinus sieboldiana var. angustata.

Planta Med. 68(11) , 1034-6, (2002)

By means of HIV gp41 binding affinity directed chromatographic fractionation, three phenylethanoid glycosides; calceolarioside A ( 1), calceolarioside B ( 2) and acteoside ( 3), along with four hydroxycoumarins; esculin ( 4), fraxin ( 5), fraxetin ( 6) and es...

[Quantitative method for simultaneous assay of four coumarins with one marker in Fraxini Cortex].

Zhongguo Zhong Yao Za Zhi 36(13) , 1782-9, (2011)

To establish a new quantitative method for simultaneous determination of multi-coumarins in Fraxini Cortex by using one chemical reference substance, and validate its feasibilities.The new quality evaluation method, quantitative analysis of multi-components b...

Metabolic fate of fraxin administered orally to rats.

J. Nat. Prod. 69(5) , 755-7, (2006)

Naturally occurring fraxin (1) was administered orally to rats to investigate its metabolism. Urinary metabolites were analyzed by three-dimensional HPLC, and fraxetin-7-O-sulfate (2), fraxetin-7-O-beta-glucuronide (3), fraxetin (4), 6,7,8-trihydroxycoumarin ...

Non-aqueous capillary electrophoresis for separation and simultaneous determination of fraxin, esculin and esculetin in Cortex fraxini and its medicinal preparations.

Biomed. Chromatogr. 19(9) , 696-702, (2005)

A non-aqueous capillary electrophoresis method has been developed for the separation and simultaneous determination of fraxin, esculin and esculetin in Cortex fraxini and its preparation for the first time. Optimum separation of the analytes was obtained on a...

Effect of organic cosolvents on the stability and activity of the beta-1,4-galactosyltransferase from bovine colostrum.

Carbohydr. Res. 305 , 525, (1998)

The influence of various organic cosolvents on the stability and activity of the beta-1,4-galactosyltransferase from bovine colostrum (GalT) and of its ancillary enzyme UDP-galactose-4'-epimerase has been investigated using the glucosylated alkaloid colchicos...

Reversed-phase HPTLC densitometric evaluation of fraxin in Fraxinus excelsior leaves.

J. Pharm. Biomed. Anal. 10(10-12) , 1089-91, (1992)

Natural compounds,fraxin and chemicals structurally related to fraxin protect cells from oxidative stress.

Exp. Mol. Med. 37(5) , 436-46, (2005)

Coumarins comprise a group of natural phenolic compounds found in a variety of plant sources. In view of the established low toxicity, relative cheapness, presence in the diet and occurrence in various herbal remedies of coumarins, it appears prudent to evalu...