2'-Deoxycytidine-5'-diphosphate trisodium salt

2'-Deoxycytidine-5'-diphosphate trisodium salt Structure
2'-Deoxycytidine-5'-diphosphate trisodium salt structure
Common Name 2'-Deoxycytidine-5'-diphosphate trisodium salt
CAS Number 151151-32-5 Molecular Weight 409.159
Density N/A Boiling Point N/A
Molecular Formula C9H14N3NaO10P2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

Looking for new pyrimidine acyclic nucleotide analogues designed for phosphorylation by human UMP-CMP kinase.

Nucleosides Nucleotides Nucleic Acids 26 , 1369-1373, (2007)

Human UMP-CMP kinase is involved in the phosphorylation of nucleic acid precursors and also in the activation of antiviral analogues including cidofovir, an acyclic phosphonate compound that mimicks dCMP and shows a broad antiviral spectrum. The binding of li...

Substrate specificity and nucleotides binding properties of NM23H2/nucleoside diphosphate kinase homolog from Plasmodium falciparum.

J. Bioenerg. Biomembr. 42 , 361-369, (2010)

Nucleoside diphosphate kinases (NDKs) play a key role in maintaining the intracellular energy resources as well as the balance of nucleotide pools. Recently, attention has been directed to NDKs owing to its role in activating various chemotherapeutic agents. ...

Structure of a halophilic nucleoside diphosphate kinase from Halobacterium salinarum.

FEBS Lett. 579 , 6595-6600, (2005)

Nucleoside diphosphate kinase from the halophilic archaeon Halobacterium salinarum was crystallized in a free state and a substrate-bound form with CDP. The structures were solved to a resolution of 2.35 and 2.2A, respectively. Crystals with the apo-form were...

Similarities and differences in the properties of multiple NDP-kinase isoforms of Alyssum murale, Ni2+-accumulator species.

J. Plant Physiol. 167 , 675-682, (2010)

Two isoforms of NDPKs (diphosphonucleoside kinases: E.C. 2.7.4.6.) named S-NDPK-A and S-NDPK-B were separated and purified from shoots of Alyssum murale (19th day of growth), a nickel accumulator plant, by a four-step procedure involving ammonium sulphate pre...