3-Methylpyrazole

3-Methylpyrazole Structure
3-Methylpyrazole structure
Common Name 3-Methylpyrazole
CAS Number 1453-58-3 Molecular Weight 82.104
Density 1.1±0.1 g/cm3 Boiling Point 204.0±0.0 °C at 760 mmHg
Molecular Formula C4H6N2 Melting Point 36 - 37ºC
MSDS Chinese USA Flash Point 87.4±11.7 °C
Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
Signal Word Danger

[Toxicological evaluation of a new nitrification inhibitor and its metabolite].

Gig. Sanit. (6) , 29-31, (1986)

Differential effects of 4-iodopyrazole and 3-methylpyrazole on the metabolic activation of methylazoxymethanol to a DNA methylating species by rat liver and rat colon mucosa in vivo.

J. Cancer Res. Clin. Oncol. 113(2) , 145-50, (1987)

Using a hybrid ion-exchange reverse phase HPLC system, we found that F344 rat liver microsomes, in the presence of an NADPH-generating system, can metabolize methylazoxymethanol (MAM), a colon and liver carcinogen, to methanol and formic acid. This is in cont...

Extremely long protection by pyrazole derivatives against chemically induced gastric mucosal injury.

J. Pharmacol. Exp. Ther. 256(2) , 592-8, (1991)

We tested the hypothesis that the gastrotoxicity of ethanol and other damaging agents is influenced through the modulation of alcohol dehydrogenase (ADH) by using either the ADH-inhibitor pyrazole or the noninhibitor derivatives of pyrazole. In time course ex...

[Structure-release relationships of active polymeric drug combinations. 1. The influence of polymer structure on the diffusion of 3-methylpyrazole from monolithic systems].

Pharmazie 40(8) , 548-52, (1985)

The release of 3-methylpyrazole from monolithic polymer films into aqueous media has been studied. The diffusion of the active agent decreased with increasing of the content of acetate groups in reacetylated poly(vinyl alcohols) and with increasing of the est...

[Structure-release relationship of physical polymer/drug combinations. 2. Diffusion of 3-methylpyrazole through a synthetic polymer matrix].

Pharmazie 41(2) , 118-20, (1986)

The diffusion of 3-methylpyrazole through a synthetic polymer matrix and the effect of the solubility of the bioactive agent in polymers on the release behaviour of polymer combinations were studied. With increasing hydrophilicity of the polymer both the diff...

Structure-release relationships of physically based polymer-biocide combinations. Part 3: Effect of the environment on the release of 3(5)-methylpyrazole from monolithic matrix systems.

Pharmazie 43(1) , 29-31, (1988)

The release behaviour of the antimicrobially active 3(5)-methylpyrazole from matrix systems prepared from maleic anhydride copolymers as well as from copolymers of maleic esters and maleic amides was studied. Under alkaline conditions erosion is the predomina...