N-Phenylnicotinamide

N-Phenylnicotinamide Structure
N-Phenylnicotinamide structure
Common Name N-Phenylnicotinamide
CAS Number 1752-96-1 Molecular Weight 198.221
Density 1.2±0.1 g/cm3 Boiling Point 265.8±13.0 °C at 760 mmHg
Molecular Formula C12H10N2O Melting Point 114-118 °C(lit.)
MSDS Chinese USA Flash Point 114.5±19.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Molluscicidal effect of nicotinanilide and its intermediate compounds against a freshwater snail Lymnaea luteola, the vector of animal schistosomiasis.

Mem. Inst. Oswaldo Cruz 99(2) , 205-10, (2004)

The molluscicidal effect of nicotinanilide was evaluated and compared with niclosamide (2',5-dichloro-4'-nitrosalicylanilide, ethanolamide salt) against different stages of the freshwater snail Lymnaea luteola i.e., eggs, immature, young mature, and adults. C...

[Preliminary studies on transaminase of Oncomelania snail].

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 8(2) , 110-2, (1990)

By paper chromatography, the tissue homogenate of Oncomelania snails was shown to form glutamic acid at the expense of alpha-ketoglutarate plus aspartic acid, alanine or arginine respectively. The existence of alanine-glutamate, aspartate-glutamate and argini...

[Evaluation of molluscicidal effect of nicotinanilide against Oncomelania snails].

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 9(3) , 216-8, (1991)

Both nicotinanilide hydrochloride and nicotinanilide sulfate are water-soluble, their IC50 and LC90 against Oncomelania snails being around 0.3 mg/L and 0.5 mg/L, respectively, during 24 hour exposure at 25 degrees C followed by a 7-day recovery period. The l...

Inhibitors of inflammation and endogenous surfactant pool size as modulators of lung injury with initiation of ventilation in preterm sheep.

Respir. Res. 11 , 151, (2010)

Increased pro-inflammatory cytokines in tracheal aspirates correlate with the development of BPD in preterm infants. Ventilation of preterm lambs increases pro-inflammatory cytokines and causes lung inflammation.We tested the hypothesis that selective inhibit...

Effects of encapsulated niacin on metabolism and production of periparturient dairy cows.

J. Dairy Sci. 94(10) , 5090-104, (2011)

Nicotinic acid (niacin) can suppress lipolysis, but responses to dietary niacin have been inconsistent in cattle. Our aim was to determine if 24 g/d of encapsulated niacin (EN; providing 9.6g/d of bioavailable nicotinic acid) alters lipid metabolism and produ...

Chronic exposure of the eggs and adults of Biomphalaria glabrata (Say) to the molluscicide, nicotinanilide.

Tropenmed. Parasitol. 34(3) , 184-6, (1983)

Some effects of chronic, low-dosage treatment of Biomphalaria glabrata eggs and adults with nicotinanilide, are reported. The susceptibility of eggs decreased with age. The development and hatching of 0-1 day old eggs could be prevented by continuous exposure...

Nicotinanilides as inhibitors of neutrophil chemotaxis.

Bioorg. Med. Chem. Lett. 12(11) , 1517-20, (2002)

A series of 4-fluoronicotinanilides was synthesized and shown to be novel, potent, and selective inhibitors against GRO-alpha-driven human neutrophil chemotaxis. Compounds of this class may be useful for the treatment of inflammatory, autoimmune, and allergic...

14N NQR study of nicotinamide and related compounds.

Magn. Reson. Chem. 46(1) , 58-62, (2008)

14N nuclear quadrupole resonance (NQR) frequencies have been measured in picolinamide, nicotinamide, isonicotinamide, 2,6-pyridine dicarboxamide, and acetamide by double resonance. The 14N NQR spectra in picolinamide, nicotinamide, isonicotinamide, and 2,6-py...

Synthesis, characterization, crystal structure and biological studies on nicotinanilide based nickel (II), copper (II) and zinc (II) complexes. Balan AMKR, et al.

Inorganica Chim. Acta 408 , 103-108, (2013)