Some effects of chronic, low-dosage treatment of Biomphalaria glabrata eggs and adults with nicotinanilide, are reported. The susceptibility of eggs decreased with age. The development and hatching of 0-1 day old eggs could be prevented by continuous exposure to 0.0005-0.001 mg/l-1 whereas prehatch stages had a susceptibility similar to that of adult snails (0.1-0.2 mg/l-1). The possible use of slow-release formulations of nicotinanilide in the control of field populations of snails and schistosomiasis transmission is discussed.