10,11-Dihydrocarbamazepine

10,11-Dihydrocarbamazepine Structure
10,11-Dihydrocarbamazepine structure
Common Name 10,11-Dihydrocarbamazepine
CAS Number 3564-73-6 Molecular Weight 238.28
Density 1.2±0.1 g/cm3 Boiling Point 394.5±52.0 °C at 760 mmHg
Molecular Formula C15H14N2O Melting Point 205-210ºC
MSDS Chinese USA Flash Point 192.4±30.7 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

Structure-activity relationship and site of binding of polyamine derivatives at the nicotinic acetylcholine receptor.

Eur. J. Biochem. 267(1) , 110-20, (2000)

Several wasp venoms contain philanthotoxins (PhTXs), natural polyamine amides, which act as noncompetitive inhibitors (NCIs) on the nicotinic acetylcholine receptor (nAChR). Effects of varying the structure of PhTXs and poly(methylene tetramine)s on the bindi...

Liquid chromatographic methods for assay of carbamazepine, 10,11-dihydrocarbamazepine, and related compounds in carbamazepine drug substance and tablets.

J. Assoc. Off. Anal. Chem. 70(5) , 836-40, (1987)

Liquid chromatographic (LC) methods have been developed for the determination of carbamazepine, the impurity 10,11-dihydrocarbamazepine, and related compounds in carbamazepine drug substance and tablets. The LC methods specify a 5 micron diol column and a mob...

An orthorhombic polymorph of 10,11-dihydrocarbamazepine.

Acta Crystallogr. C 62(Pt 5) , o240-2, (2006)

The title compound (systematic name: 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide), C15H14N2O, is shown to crystallize as an orthorhombic polymorph to complement the known monoclinic form. The molecular conformations of both forms are very similar, invol...

Determination of carbamazepine and its epoxide metabolite in plasma by high-speed liquid chromatography.

J. Chromatogr. A. 103(1) , 135-40, (1975)

A liquid-chromatographic method for the simultaneous determination of carbamazepine and its active metabolite (carbamazepine 10,11-epoxide) in plasma has been developed. The two compounds were identified in plasma by mass spectrometry. The lower limit of sens...

A predicted dimer-based polymorph of 10, 11-dihydrocarbamazepine (Form IV). Arlin J-B, et al.

CrystEngComm 12(1) , 64-66, (2010)

Determination of carbamazepine by chemiluminescence detection using chemically prepared tris(2,2'-bipyridine)ruthenium(III) as oxidant.

Anal. Sci. 19(6) , 903-6, (2003)

A new chemiluminescence method for the determination of carbamazepine (CBZ) has been developed. The method is based on the chemiluminescence produced in the reaction of tris(2,2'-bipyridine)ruthenium(III) and CBZ in an acidic medium. The chemiluminescence int...