Potassium phthalimide
Potassium phthalimide structure
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Common Name | Potassium phthalimide | ||
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| CAS Number | 1074-82-4 | Molecular Weight | 185.221 | |
| Density | 1.367g/cm3 | Boiling Point | 359ºC at 760 mmHg | |
| Molecular Formula | C8H4KNO2 | Melting Point | >300°C | |
| MSDS | USA | Flash Point | 170.9ºC | |
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Synthesis and anti-angiogenic activity of benzothiazole, benzimidazole containing phthalimide derivatives.
Bioorg. Med. Chem. Lett. 23(1) , 287-90, (2013) Benzothiazole and benzimidazole containing phthalimide derivatives (NK037, NK041, NK042, NK0139A and NK0148) have been synthesized and their anti-angiogenic activity was evaluated using ex vivo egg yolk angiogenesis model. A comparative study with pure thalid... |
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Azolyacetones as precursors to indoles and naphthofurans facilitated by microwave irradiation with simultaneous cooling.
Molecules 14(8) , 2976-84, (2009) Phthalimide reacted with phenacyl bromide under microwave irradiation to yield phenacyl isoindolidene-1,3-dione (3b), while 3a reacted with phenylhydrazine to yield the phenylhydrazone 4 that was readily converted into indoylphthalimide 8. Similarly N-benzotr... |
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A review of methods for the analysis of orphan and difficult pesticides: glyphosate, glufosinate, quaternary ammonium and phenoxy acid herbicides, and dithiocarbamate and phthalimide fungicides.
J. AOAC Int. 97(4) , 965-77, (2014) This article reviews the chromatography/MS methodologies for analysis of pesticide residues of orphan and difficult chemical classes in a variety of sample matrixes including water, urine, blood, and food. The review focuses on pesticide classes that are not ... |
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Novel anilinophthalimide derivatives as potential probes for beta-amyloid plaque in the brain.
Bioorg. Med. Chem. 18 , 1337-43, (2010) A group of novel 4,5-dianilinophthalimide derivatives has been synthesized in this study for potential use as beta-amyloid (Abeta) plaque probes. Staining of hippocampus tissue sections from Alzheimer's disease (AD) brain with the representative compound 9 in... |
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Synthesis and in vitro cytotoxic evaluation of N-alkylbromo and N-alkylphthalimido-isatins.
Bioorg. Med. Chem. Lett. 21 , 3017-20, (2011) The manuscript pertains to the synthesis and in vitro cytotoxic evaluation of a series of N-alkylbromo and N-alkylphthalimido-isatins against four different human cancer cell lines namely Colon: HCT-15; Liver: Hep-2; Lung: A-549 and Leukemia: THP-1 at 10 and ... |
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Synthesis and in vitro anti Mycobacterium tuberculosis activity of a series of phthalimide derivatives.
Bioorg. Med. Chem. 17 , 3795-9, (2009) New phthalimide derivatives were easily prepared through condensation of phthalic anhydride and selected amines with variable yields (70-90%). All compounds (3a-l) were evaluated against Mycobacterium tuberculosis H(37)Rv using Alamar Blue susceptibility. The... |
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Strong two photon absorption and photophysical properties of symmetrical chromophores with electron accepting edge substituents.
J. Phys. Chem. A 112(21) , 4742-8, (2008) Two photon absorption (TPA) and photophysical properties of three new symmetrical chromophores with electron accepting phthalimide edge substituents have been studied. The three chromophores contain fluorene, alcoxy-substituted divinyl benzene, and carbazole ... |
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Using light to covalently immobilize and pattern nanoparticles onto surfaces.
Langmuir 28(29) , 10934-41, (2012) There is considerable current interest in developing methods to integrate nanoparticles into optical, electronic, and biological systems due to their unique size-dependent properties and controllable shape. We report herein a versatile new approach for covale... |
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Dissociation of aryl sulfonyl phthalimide radical anions: relevance to the biological activity of aryl sulfonyl amides.
Chem. Commun. (Camb.) 48(92) , 11328-30, (2012) The reduction of two aryl sulfonyl phthalimides leads to the corresponding radical anions. Surprisingly, that of the nitro-derivative decomposes faster than that of the methyl derivative. A theoretical investigation along with application of the dissociative ... |
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Novel derivatives of ISO-1 as potent inhibitors of MIF biological function.
Bioorg. Med. Chem. Lett. 19(16) , 4773-6, (2009) A series of novel 1,2,4-oxadiazole, phthalimide, amide and other derivatives of ISO-1 were synthesized and probed for inhibition of macrophage migration inhibitory factor (MIF) activity. Several compounds inhibited MIF enzymatic activity at levels better than... |