methoxamine hydrochloride
methoxamine hydrochloride structure
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Common Name | methoxamine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 61-16-5 | Molecular Weight | 247.71900 | |
| Density | N/A | Boiling Point | 368.4ºC at 760 mmHg | |
| Molecular Formula | C11H18ClNO3 | Melting Point | 212-216ºC | |
| MSDS | USA | Flash Point | 176.6ºC | |
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Role of 5-HT7 receptors in the inhibition of the vasodepressor sensory CGRPergic outflow in pithed rats
Vascul. Pharmacol. 63(1) , 4-12, (2014) The role of calcitonin gene-related peptide (CGRP) in the modulation of vascular tone has been widely documented. Indeed, electrical stimulation of the perivascular sensory outflow in pithed rats induces vasodepressor responses by activation of CGRP receptors... |
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Lipophilicity of amine neurotransmitter precursors, metabolites and related drugs estimated on various TLC plates.
J. Chromatogr. Sci. 52(9) , 1095-103, (2014) The retention behavior for a series of amine neurotransmitters, their precursors, metabolites and structurally related drugs has been investigated in reversed-phase thin-layer chromatography using RP-18, RP-8, RP-2, CN and Diol stationary phases and mixtures ... |
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Mechanisms of vasorelaxation to gamma-mangostin in the rat aorta.
J. Med. Assoc. Thai. 95 Suppl 12 , S63-8, (2012) To investigate the effects of gamma-mangostin on vascular tone and its mechanisms in the isolated rat aorta.Aortic rings from male Wistar rats were precontracted with methoxamine. Changes in tension were measured using an isometric force transducer and record... |
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Effects of Phikud Navakot extract on vascular reactivity in the isolated rat aorta.
J. Med. Assoc. Thai. 95 Suppl 12 , S1-7, (2012) The aim of the present study is to investigate the effect of standardized Phikud Navakot extract (NVKE) on aortic rings from male Sprague Dawley rats. Changes in tension were measured using an isometric force transducer and recorded on the PowerLab recording ... |
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Gas chromatography time-of-flight mass spectrometry (GC-TOF-MS)-based metabolomics for comparison of caffeinated and decaffeinated coffee and its implications for Alzheimer's disease.
PLoS ONE 9(8) , e104621, (2014) Findings from epidemiology, preclinical and clinical studies indicate that consumption of coffee could have beneficial effects against dementia and Alzheimer's disease (AD). The benefits appear to come from caffeinated coffee, but not decaffeinated coffee or ... |
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Effect of severe acidosis on vasoactive effects of epinephrine and norepinephrine in human distal mammary artery.
J. Thorac. Cardiovasc. Surg. 147(5) , 1698-705, (2014) Acidosis is a very common pathologic process in perioperative management. However, how to correct severe acidosis to improve the efficacy of vasoconstrictors in hemodynamically unstable patients is still debated. The present study investigated whether severe ... |
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The effect of high-fructose intake on the vasopressor response to angiotensin II and adrenergic agonists in Sprague-Dawley rats.
Pak. J. Pharm. Sci. 26(4) , 727-32, (2013) Effect of losartan was assessed on systemic haemodynamic responses to angiotensin II (Ang II) and adrenergic agonists in the model of high-fructose-fed rat. Twenty-four Sprague-Dawley (SD) rats were fed for 8 weeks either 20% fructose solution (FFR) or tap wa... |
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Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons.
Neuropharmacology 88 , 110-21, (2014) The ventral tegmental area (VTA) plays an important role in reward and motivational processes involved in drug addiction. Previous studies have shown that alpha1-adrenoreceptors (α1-AR) are primarily found pre-synaptically at this area. We hypothesized that G... |
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Impaired retinal vasodilator response to acetylcholine in a rat model of NMDA-induced retinal degeneration.
J. Pharmacol. Sci. 127(2) , 211-6, (2015) Previous studies have shown that degeneration of retinal capillaries occurs following N-methyl-D-aspartate (NMDA)-induced retinal neurotoxicity, but it is unclear whether vasodilatory mechanisms are altered in retinal blood vessels. The purpose of the present... |
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Involvement of perivascular nerves and transient receptor potential vanilloid 1 (TRPV1) in vascular responses to histamine in rat mesenteric resistance arteries.
Eur. J. Pharmacol. 680(1-3) , 73-80, (2012) A previous report showed that histamine in denuded mesenteric vascular beds produced a triphasic response; an initial small histamine H(2) receptor-mediated vasodilation, a transient histamine H(1) receptor-mediated vasoconstriction, and finally a long-lastin... |