1-Bromo-2-chloroethane

1-Bromo-2-chloroethane Structure
1-Bromo-2-chloroethane structure
Common Name 1-Bromo-2-chloroethane
CAS Number 107-04-0 Molecular Weight 143.410
Density 1.7±0.1 g/cm3 Boiling Point 106.7±0.0 °C at 760 mmHg
Molecular Formula C2H4BrCl Melting Point −18-−14 °C(lit.)
MSDS Chinese USA Flash Point 9.5±8.5 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Simultaneous derivatization and solid-based disperser liquid-liquid microextraction for extraction and preconcentration of some antidepressants and an antiarrhythmic agent in urine and plasma samples followed by GC-FID.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 983-984 , 55-61, (2015)

The present work is based on a one-step method including derivatization and solid-based disperser liquid-liquid microextraction followed by gas chromatography-flame ionization detection (GC-FID) for the determination of four antidepressants (fluoxetine, fluvo...

Efficient synthesis of furan-2-ylacetates, 7-(alkoxycarbonyl)benzofurans, and 7-(alkoxycarbonyl)-2,3-dihydrobenzofurans based on cyclization reactions of free and masked dianions: a "cyclization/dehydrogenation" strategy.

J. Org. Chem. 70 , 10013-10029, (2005)

[reaction: see text] A variety of furan-2-ylacetates have been prepared by dehydrogenation of monocyclic 2-alkylidenetetrahydrofurans, which are readily available by cyclizations of open-chained 1,3-dicarbonyl dianions with 1-bromo-2-chloroethane. 5'H-[2,3']B...

Regio- and diastereoselective synthesis of 2-alkylidenetetrahydrofurans by domino SN/SN' and SN/SN reactions of 1,3-dicarbonyl dianions.

J. Org. Chem. 66(18) , 6057-63, (2001)

The domino C,O-cyclodialkylation reaction of dilithiated 1,3-dicarbonyl compounds with 1,4-dibromo-2-butene resulted in regio- and diastereoselective formation of 2-alkylidene-5-vinyltetrahydrofurans. The cyclization of 1,3-dicarbonyl dianions with 1-bromo-2-...

Dissociative double ionization of 1-bromo-2-chloroethane irradiated by an intense femtosecond laser field.

J. Chem. Phys. 135(6) , 064303, (2011)

The dissociative double ionization and multi-photon ionization of 1-bromo-2-chloroethane (BCE) irradiated by the 800 nm femtosecond laser field have been investigated by dc-slice imaging technology. The charged parent ion ratio [BCE(2+)]/[BCE(+)] was measured...

A conformational study of 1-bromo-2-chloroethane in zeolites.

Langmuir 25(14) , 8042-50, (2009)

The conformational properties of 1-bromo-2-chloroethane (BCE) in several representative zeolites including silicalite-1, siliceous Y (Si-Y), Na-Y, and zeolite L have been investigated by FT-Raman spectroscopy in combination with thermogravimetric analysis. Th...

Characterization of the genotoxic action of three structurally related 1,2-dihaloalkanes in Drosophila melanogaster.

Mutat. Res. 285(2) , 209-17, (1993)

The genetic activity profiles of three structurally related dihaloalkanes, 1,2-dibromoethane (DBE), 1,2-dichloroethane (DCE) and 1-bromo-2-chloroethane (BCE), were compared in germ cells and somatic tissue of Drosophila melanogaster. The two genotoxicity indi...

Mutation spectra of 1,2-dibromoethane, 1,2-dichloroethane and 1-bromo-2-chloroethane in excision repair proficient and repair deficient strains of Drosophila melanogaster.

Carcinogenesis 15(5) , 869-75, (1994)

DNA sequence changes produced by 1,2-dibromoethane (DBE), 1,2-dichloroethane (DCE) and 1-bromo-2-chloroethane (BCE) were analyzed using the vermilion locus of Drosophila melanogaster. Under excision repair proficient (exr+) conditions (mutagenized exr+ males ...

Coherent control of the ultrafast dissociative ionization dynamics of bromochloroalkanes.

Phys. Chem. Chem. Phys. 13(19) , 8705-14, (2011)

We report on the coherent control of the ultrafast ionization and fragmentation dynamics of the bromochloroalkanes C(2)H(4)BrCl and C(3)H(6)BrCl using shaped femtosecond laser pulses. In closed-loop control experiments on bromochloropropane (C(3)H(6)BrCl) the...

A new Salmonella typhimurium NM5004 strain expressing rat glutathione S-transferase 5-5: use in detection of genotoxicity of dihaloalkanes using an SOS/umu test system.

Carcinogenesis 17(2) , 297-302, (1996)

The Escherichia coli mu operon was subcloned into a pKK233-2 vector containing rat glutathione S-transferase (GST) 5-5 cDNA and the plasmid thus obtained was introduced into Salmonella typhimurium TA1535. The newly developed strain S.typhimurium NM5004, was f...

Comparative in vivo genotoxicity and acute hepatotoxicity of three 1,2-dihaloethanes.

Carcinogenesis 4(11) , 1491-4, (1983)

Hepatic DNA damage was demonstrated by alkaline DNA unwinding/hydroxylapatite batch chromatography in male B6C3F1 mice treated with non-necrogenic doses of 1,2-dichloroethane, 1-bromo-2-chloroethane, and 1,2-dibromoethane. Intraperitoneal administration of 0....