CISAPRIDEMONOHYDRATE

CISAPRIDEMONOHYDRATE Structure
CISAPRIDEMONOHYDRATE structure
Common Name CISAPRIDEMONOHYDRATE
CAS Number 260779-88-2 Molecular Weight 483.96
Density N/A Boiling Point N/A
Molecular Formula C23H31ClFN3O5 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS05
GHS05
Signal Word Danger

Acute cardiotoxicity evaluation of the marine biotoxins OA, DTX-1 and YTX.

Toxins (Basel.) 7 , 1030-47, (2015)

Phycotoxins are marine toxins produced by phytoplankton that can get accumulated in filter feeding shellfish. Human intoxication episodes occur due to contaminated seafood consumption. Okadaic acid (OA) and dynophysistoxins (DTXs) are phycotoxins responsible ...

High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Hepatocytes.

Assay Drug Dev. Technol. 13 , 529-46, (2015)

Cell-based high-content screening (HCS) assays have become an increasingly attractive alternative to traditional in vitro and in vivo testing in pharmaceutical drug development and toxicological safety assessment. The time- and cost-effectiveness of HCS assay...

A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.

Assay Drug Dev. Technol. 8 , 714-26, (2010)

The voltage-gated potassium channel, human Ether-à-go-go related gene (hERG), represents the molecular component of IKr, one of the potassium currents involved in cardiac action potential repolarization. Inhibition of IKr increases the duration of the ventric...

Cisapride and structural analogs selectively enhance 5-hydroxytryptamine (5-HT)-induced purinergic neurotransmission in the guinea pig proximal colon.

J. Pharmacol. Exp. Ther. 274 , 641-648, (1995)

In the guinea pig proximal colon, 5-hydroxytryptamine (5-HT) stimulates neuronal 5-HT1-like receptors to induce relaxations that are mediated by nitric oxide and ATP. In the current study, the effects of cisapride and structural analogs on these 5-HT-induced ...

Effects of mosapride citrate, a 5-HT4 receptor agonist, on colonic motility in conscious guinea pigs.

Jpn. J. Pharmacol. 90 , 313-320, (2002)

It is known that 5-HT(4) receptors in the colon of guinea pigs show a distribution similar to that in humans. Thus, we examined the effects of mosapride citrate (mosapride) and cisapride, two 5-HT(4)-receptor agonists, on colonic motility in conscious guinea ...

Cholinergic neurotransmission participates in increased food intake induced by NMDA receptor blockade.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 285 , R641-R648, (2003)

MK-801, a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, enhances gastric emptying while increasing food intake. Although our previously reported results implicate the vagus in MK-801's effect on feeding, it is not clear whether vagal motor f...