(L)-Canavanine
(L)-Canavanine structure
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Common Name | (L)-Canavanine | ||
|---|---|---|---|---|
| CAS Number | 543-38-4 | Molecular Weight | 176.17 | |
| Density | 1.61g/cm3 | Boiling Point | 431.2ºC at 760mmHg | |
| Molecular Formula | C5H12N4O3 | Melting Point | 184ºC | |
| MSDS | Chinese USA | Flash Point | 214.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Rad23 interaction with the proteasome is regulated by phosphorylation of its ubiquitin-like (UbL) domain.
J. Mol. Biol. 426(24) , 4049-60, (2014) Rad23 was identified as a DNA repair protein, although a role in protein degradation has been described. The protein degradation function of Rad23 contributes to cell cycle progression, stress response, endoplasmic reticulum proteolysis, and DNA repair. Rad23... |
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Shrimp waste extract and astaxanthin: rat alveolar macrophage, oxidative stress and inflammation.
J. Food Sci. 77(7) , H141-6, (2012) Astaxanthin is a carotenoid known to have antioxidant and antiinflammatory properties. This study examined if shrimp astaxanthin modulates the production of superoxide (O(-)(2)), nitric oxide (NO), and tumor necrosis factor-α (TNF-α) in rat alveolar macrophag... |
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Interactions between phytochemical components of Sutherlandia frutescens and the antiretroviral, atazanavir in vitro: implications for absorption and metabolism.
J. Pharm. Pharm. Sci. 15(2) , 221-33, (2012) African traditional medicinal plants, such as Sutherlandia frutescens have the potential to interact pharmacokinetically with the protease inhibitor class of antiretrovirals, thereby impacting on their safety and efficacy. The effects of extracts and phytoche... |
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Quantification of canavanine, 2-aminoethanol, and cyanamide in Aphis craccivora and its host plants, Robinia pseudoacacia and Vicia angustifolia: effects of these compounds on larval survivorship of Harmonia axyridis.
J. Chem. Ecol. 38(12) , 1552-60, (2012) The cowpea aphid Aphis craccivora that infests the black locust Robinia pseudoacacia shows toxicity to its predator, the multicolored Asian ladybird beetle, Harmonia axyridis. In contrast, the same aphid species that infests the common vetch, Vicia angustifol... |
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Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity.
Mol. Biochem. Parasitol. 198(1) , 29-36, (2014) Nitric oxide (NO) accumulates in Plasmodium falciparum-infected erythrocytes. It may be produced by a parasite NO synthase (NOS) or by nitrate reduction. The parasite's benefit of NO accumulation is not understood. We investigated if inhibiting the P. falcipa... |
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Physiological consequences of mutations in the htpG heat shock gene of Escherichia coli.
Mutat. Res. 745-746 , 1-5, (2013) Mutation of the heat shock gene, htpG, causes severe defects of several cellular functions in Escherichia coli. A null htpG mutant constructed by gene replacement was impaired in the biosynthesis and secretion of several enzymes, and in biofilm formation and ... |
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Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapy.
Proc. Natl. Acad. Sci. U. S. A. 109(50) , E3434-43, (2012) Cystinosin, the lysosomal cystine exporter defective in cystinosis, is the founding member of a family of heptahelical membrane proteins related to bacteriorhodopsin and characterized by a duplicated motif termed the PQ loop. PQ-loop proteins are more frequen... |
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Characterization and isolation of mutants producing increased amounts of isoamyl acetate derived from hygromycin B-resistant sake yeast.
Biosci. Biotechnol. Biochem. 76(1) , 60-6, (2012) Hygromycin B is an aminoglycoside antibiotic that inhibits protein synthesis in prokaryotes and eukaryotes. Twenty-four hygromycin B-resistants mutants were isolated from sake yeast, and were divided into three different degrees of strength according to hygro... |
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The crystal structure of arginyl-tRNA synthetase from Homo sapiens.
FEBS Lett. 588(14) , 2328-34, (2014) Arginyl-tRNA synthetase (ArgRS) is a tRNA-binding protein that catalyzes the esterification of L-arginine to its cognate tRNA. L-Canavanine, a structural analog of L-arginine, has recently been studied as an anticancer agent. Here, we determined the crystal s... |
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Screening for long-lived genes identifies Oga1, a guanine-quadruplex associated protein that affects the chronological lifespan of the fission yeast Schizosaccharomyces pombe.
Mol. Genet. Genomics 288(5-6) , 285-95, (2013) Schizosaccharomyces pombe and Saccharomyces cerevisiae are excellent model organisms to study lifespan. We conducted screening to identify novel genes that, when overexpressed, extended the chronological lifespan of fission yeast. We identified seven genes, a... |