Ethylurea
Ethylurea structure
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Common Name | Ethylurea | ||
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| CAS Number | 625-52-5 | Molecular Weight | 88.10840 | |
| Density | 1.005 g/cm3 | Boiling Point | 136.3ºC at 760 mmHg | |
| Molecular Formula | C3H8N2O | Melting Point | 87-90 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 93 °C | |
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Solvation of human serum albumin in aqueous alkylurea solutions.
Int. J. Pept. Protein Res. 42(4) , 320-5, (1993) Solvation of human serum albumin in aqueous solutions of urea, methyl-, N,N'-dimethyl-, and ethylurea was studied by density measurements. From the densities at constant molality and constant chemical potential, the preferential solvation parameters of human ... |
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Inhibition of HIV-1 infection by alkylureas.
AIDS 5(12) , 1447-52, (1991) The risk of infection by HIV-1 through transfusion of contaminated blood products has been markedly decreased but not eliminated by serological screening of donors. Methods are required to further minimize or eliminate the risk of infection of blood product r... |
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Neoplasia induced in male rats fed lead acetate, ethyl urea, and sodium nitrite.
Toxicol. Pathol. 13(1) , 50-7, (1985) Sprague-Dawley rats were exposed to 0, 26, or 2600 ppm lead as lead acetate in drinking water for 76 weeks. At 28 weeks of lead exposure, a portion of each group was exposed simultaneously to 6.36 g/kg ethyl urea (EU) and 2.0 g/kg sodium nitrite (NaNO2) for a... |
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Mutagenic effects of nitrogen dioxide combined with methylurea and ethylurea in Drosophila melanogaster.
Mutat. Res. 88(3) , 281-90, (1981) The standard sex-linked recessive lethal test was used to test whether NO2 induces lethal mutations in male germ cells of Drosophila in the presence or absence of alkylureas. Methylurea, ethylurea and NO2 alone did not enhance the mutation frequency significa... |
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Comparison of nicotinamide, ethylurea and polyethylene glycol as carriers for nifedipine solid dispersion systems.
Chem. Pharm. Bull. 45(10) , 1688-93, (1997) The most prevalent means for producing solid dispersions of nifedipine, a poorly water-soluble drug, are the solvent based processes that bring problems of environmental and health. We have investigated the preparation of solid dispersions of nifedipine (mp 1... |
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Alterations in the reproductive performance of habrobracon females following combined treatments with ethylurea and sodium nitrate or nitrite.
Mutat. Res. 88(2) , 179-89, (1981) Ethylurea (EU) and NaNO2 fed simultaneously to female braconid wasps caused several types of changes in reproductive performance. Early effects included a decrease in (a) the number of vitellogenic oocytes developing into eggs, and in (b) the hatchability of ... |
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Compactness of the molten globule in comparison to unfolded states as observed by size-exclusion chromatography.
Biochim. Biophys. Acta 1209(1) , 140-3, (1994) The volumes of elution of denatured states of four proteins at high urea (8 M) and ethylurea (6 M) concentration were determined. They were found equally unfolded in both solvents. The volumes of elution of the unfolded states were compared to those of the na... |
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Teratogenic effect of extended administration of N-nitrosoethylurea and ethylurea/nitrite in rats.
Res. Commun. Chem. Pathol. Pharmacol. 41(2) , 265-81, (1983) N-Nitrosoethylurea (ENU) and ethylurea (EU) with sodium nitrite (NaNO2) were administered daily by mouth to Hooded Wistar rats. Doses ranged from 1-50 mg ENU/kg body weight (day-1) and from 20-70 mg EU/kg body weight day-1 and extended over days 7 to 16 inclu... |
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Membrane interactions of a new class of anticancer agents derived from arylchloroethylurea: a FTIR spectroscopic study.
Chem. Phys. Lipids 111(2) , 163-75, (2001) We have investigated the interaction between a new class of antineoplastic agents derived from arylchloroethylurea (CEU) and different lipids such as dimyristoylphosphatidylcholine (DMPC) in the absence and presence of 30 mol% of cholesterol, dimyristoylphosp... |
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N-4-iodophenyl-N'-2-chloroethylurea, a novel potential anticancer agent with colon-specific accumulation: radioiodination and comparative in vivo biodistribution profiles.
Invest. New Drugs 28(2) , 124-31, (2010) In a search for more selective anticancer drugs, we have designed nitrogen mustard and nitrosourea conjugates leading to a series of N-4-aryl-N'-2-chloroethylureas (CEUs). The iodinated derivative N-4-iodophenyl-N'-2-chloroethylurea (4-ICEU) has demonstrated ... |