5'-O-Dimethoxytrityl-deoxythymidine
5'-O-Dimethoxytrityl-deoxythymidine structure
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Common Name | 5'-O-Dimethoxytrityl-deoxythymidine | ||
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| CAS Number | 40615-39-2 | Molecular Weight | 528.596 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C31H32N2O7 | Melting Point | 114-116 °C (subl.)(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method.
Nucleic Acids Res. 8(22) , 5473-89, (1980) Synthesis of two oligothymidylic acids, tridecamer and nonadecamer, is described by a rapid and simple solid-phase method on two kinds of polyacrylamide supports derivatized from commercially available Enzacryl Gel K-2. The syntheses were performed by the pho... |
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Synthesis of mixed oligodeoxyribonucleotides following the solid phase method.
Nucleic Acids Res. 10(10) , 3291-301, (1982) A method for the synthesis of mixed dimers, trimers and oligonucleotides on a solid support using monomeric protected nucleoside phosphochloridites (1a-d) has been developed and the different nucleoside reagents, and the results show that yields of different ... |
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Synthesis of 14 C-radiolabeled oligonucleotides with a novel phosphoramidite reagent.
Bioorg. Med. Chem. Lett. 8(9) , 1123-6, (1998) A novel solid-phase synthesis of 5'-radiolabeled oligonucleotides is described. The labeling reaction is carried out by the phosphoramidite method with the aid of [4,6-di-14C]-5'-dimethoxytritylthymidine building block 1. The feasibility of the method is demo... |
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Nucleotides part LXXX: Synthesis of 3'-O fluorescence labeled thymidine derivatives and their 5'-O-triphosphates.
Nucleosides Nucleotides Nucleic Acids 30(7-8) , 544-51, (2011) A new labeling technique attaching a fluorescent pteridine derivative (3, 5) via a linker onto the 3'-OH group of 5'-O-dimethoxytritylthymidine (7) was developed to lead to the conjugates 8 and 11. After detritylation to give 9 and 12, the final conversion in... |
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Aldrichimica Acta 20 , 52, (1987)
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Oligodeoxynucleotide analogues containing 3'-deoxy-3'-C- threo-hydroxymethylthymidine: Synthesis, hybridization properties and enzymatic stability. Svendsen ML, et al.
Tetrahedron 49(48) , 11341-52, (1993)
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