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5'-O-(4,4'-二甲氧基三苯甲基)胸苷

5'-O-(4,4'-二甲氧基三苯甲基)胸苷结构式
5'-O-(4,4'-二甲氧基三苯甲基)胸苷结构式
品牌特惠专场
常用名 5'-O-(4,4'-二甲氧基三苯甲基)胸苷 英文名 5'-O-Dimethoxytrityl-deoxythymidine
CAS号 40615-39-2 分子量 528.596
密度 1.2±0.1 g/cm3 沸点 N/A
分子式 C31H32N2O7 熔点 114-116 °C (subl.)(lit.)
MSDS 中文版 美版 闪点 N/A

Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method.

Nucleic Acids Res. 8(22) , 5473-89, (1980)

Synthesis of two oligothymidylic acids, tridecamer and nonadecamer, is described by a rapid and simple solid-phase method on two kinds of polyacrylamide supports derivatized from commercially available Enzacryl Gel K-2. The syntheses were performed by the pho...

Synthesis of mixed oligodeoxyribonucleotides following the solid phase method.

Nucleic Acids Res. 10(10) , 3291-301, (1982)

A method for the synthesis of mixed dimers, trimers and oligonucleotides on a solid support using monomeric protected nucleoside phosphochloridites (1a-d) has been developed and the different nucleoside reagents, and the results show that yields of different ...

Synthesis of 14 C-radiolabeled oligonucleotides with a novel phosphoramidite reagent.

Bioorg. Med. Chem. Lett. 8(9) , 1123-6, (1998)

A novel solid-phase synthesis of 5'-radiolabeled oligonucleotides is described. The labeling reaction is carried out by the phosphoramidite method with the aid of [4,6-di-14C]-5'-dimethoxytritylthymidine building block 1. The feasibility of the method is demo...

Nucleotides part LXXX: Synthesis of 3'-O fluorescence labeled thymidine derivatives and their 5'-O-triphosphates.

Nucleosides Nucleotides Nucleic Acids 30(7-8) , 544-51, (2011)

A new labeling technique attaching a fluorescent pteridine derivative (3, 5) via a linker onto the 3'-OH group of 5'-O-dimethoxytritylthymidine (7) was developed to lead to the conjugates 8 and 11. After detritylation to give 9 and 12, the final conversion in...

Aldrichimica Acta 20 , 52, (1987)

Oligodeoxynucleotide analogues containing 3'-deoxy-3'-C- threo-hydroxymethylthymidine: Synthesis, hybridization properties and enzymatic stability. Svendsen ML, et al.

Tetrahedron 49(48) , 11341-52, (1993)