Astilbin
Astilbin structure
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Common Name | Astilbin | ||
|---|---|---|---|---|
| CAS Number | 29838-67-3 | Molecular Weight | 450.393 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 801.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C21H22O11 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 282.9±27.8 °C | |
| Symbol |
GHS09 |
Signal Word | Warning | |
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Isolation and characterization of two flavonoids, engeletin and astilbin, from the leaves of Engelhardia roxburghiana and their potential anti-inflammatory properties.
J. Agric. Food Chem. 59(9) , 4562-9, (2011) Engeletin, a flavonoid compound, was isolated from the leaves of Engelhardia roxburghiana for the first time, along with astilbin, another flavonoid. The chemical structures of engeletin and astilbin were confirmed by (1)H and (13)C nuclear magnetic resonance... |
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ACE inhibition by astilbin isolated from Erythroxylum gonocladum (Mart.) O.E. Schulz.
Phytomedicine 17(5) , 383-7, (2010) Erythroxylum species have several traditional uses in different countries, including the treatment of hypertension. The ethanol extract from E. gonocladum aerial parts, a species endemic to the Brazilian cerrado, elicited a concentration-dependent inhibition ... |
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Chemical constituents comparison between Rhizoma Smilacis Glabrae and Rhizoma Smilacis Chinae by HPLC-DAD-MS/MS.
Nat. Prod. Res. 27(3) , 277-81, (2013) Rhizoma Smilacis Glabrae (RSG) and Rhizoma Smilacis Chinae (RSC) are two herbal materials that belong to the same genera and are both listed in the Chinese Pharmacopoeia. Chemical constituents in the two species were compared by HPLC-DAD-MS/MS. Many common co... |
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Induction of TGF-_ and IL-10 production in dendritic cells using astilbin to inhibit dextran sulfate sodium-induced colitis.
Biochem. Biophys. Res. Commun. 446(2) , 529-34, (2014) Astilbin, a major bioactive compound from Rhizoma smilacis glabrae, has been reported to possess anti-inflammatory properties. Our study first evaluated astilbin on dextran sulfate sodium (DSS)-induced acute colitis in mice. By intraperitoneal injection of as... |
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Effect of astilbin on experimental diabetic nephropathy in vivo and in vitro.
Planta Med. 75(14) , 1470-5, (2009) Astilbin, a flavonoid compound, was isolated from the rhizome of Smilax glabra Roxb. This study was conducted to investigate the efficacy of astilbin on experimental diabetic nephropathy (DN) in vivo and in vitro and its possible mechanisms. Astilbin was adde... |
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Development of HPLC fingerprint for species differentiation and quality assessment of Rhizoma Smilacis Glabrae.
J. Nat. Med. 67(1) , 207-11, (2013) Rhizoma Smilacis Glabrae (RSG) is a commonly used herbal material in functional food and Traditional Chinese Medicine. A HPLC chromatographic fingerprint was developed for its quality control and species differentiation. Nine peaks were found in the chromatog... |
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Structural revision of two flavanonol glycosides from Smilax glabra.
Planta Med. 75(6) , 654-5, (2009) The structures of two flavanonol glycosides isolated from Smilax glabra, named smitilbin and neosmitilbin, have been revised to isoastilbin and neoastilbin, respectively. The revised structures were determined based on intensive studies of chemical interconve... |
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Validation and application of an LC-ESI-MS method for simultaneous determination of astilbin and its major metabolite 3'-O-methylastilbin in rat plasma.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(18-19) , 1765-70, (2009) We herein describe the development of an LC-MS method for simultaneous determination of astilbin and 3'-O-methylastilbin in rat plasma. A simple liquid-liquid extraction procedure was followed by injection of the extracts on to a Shim-pack C(18) column (150 m... |
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Inhibition of peroxidase activity and scavenging of reactive oxygen species by astilbin isolated from Dimorphandra mollis (Fabaceae, Caesalpinioideae).
Biol. Res. 43(1) , 63-74, (2010) Astilbin (5,7,3',4'-tetrahydroxy-2,3-dihydroflavonol-3-ß-o-rhamnoside), a flavonoid with a large range of biological activities, was isolated from Dimorphandra mollis, a shrub common to the Brazilian Cerrado. The purpose of this study is to verify the effects... |
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Chemical constituents of Bauhinia aurea.
J. Asian Nat. Prod. Res. 14(10) , 966-72, (2012) A new dihydroflavonol glycoside dimer 6,6-bisastilbin (1) and a new nitrile-containing metabolite (Z)-5α,6β-dihydroxy-4β-methoxy-2-cyclohexene-Δ(1,α)-acetonitrile (2), together with three known analogs, bauhinin, bauhinilide, and dehydrodicatechin A, have bee... |