Oxymetazoline hydrochloride
Oxymetazoline hydrochloride structure
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Common Name | Oxymetazoline hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 2315-02-8 | Molecular Weight | 296.836 | |
| Density | 1.08g/cm3 | Boiling Point | 431.9ºC at 760mmHg | |
| Molecular Formula | C16H25ClN2O | Melting Point | >270°C (分解) | |
| MSDS | Chinese USA | Flash Point | 215ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Cilazapril stability in the presence of hydrochlorothiazide in model mixtures and fixed dose combination.
Acta Pol. Pharm. 70(6) , 1079-85, (2013) The presented study aimed at the evaluation of hydrochlorothiazide influence on cilazapril stability in model mixture and fixed dose tablet formulation. The degradation of cilazapril in the presence of hydrochlorothiazide took place according to autocatalytic... |
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Selectivity of the imidazoline alpha-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned alpha 1-adrenoceptor subtypes.
Br. J. Pharmacol. 116 , 1611, (1995) 1. To investigate the structure-activity relationships of alpha-adrenoceptor agonists for the alpha 1-adrenoceptor subtypes, we have compared the imidazoline class of compounds, oxymetazoline and cirazoline, with the phenethylamine, noradrenaline, in their af... |
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Interaction of the alpha-adrenoceptor agonist oxymetazoline with serotonin 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors.
Eur. J. Pharmacol. 196 , 213, (1991) Oxymetazoline was recognized with nanomolar affinity by 5-HT1A, 5-HT1B and 5-HT1D binding sites and mimicked the effects of 5-hydroxytryptamine with about the same potency and intrinsic activity as the endogenous amine in the corresponding functional tests. A... |
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Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation.
J. Med. Chem. 41 , 2243-2251, (1998) Benzylimidazolines may represent a class of 5-HT1D ligands that has yet to be exploited. On the basis of a previous report that the 2-(substituted-benzyl)imidazoline alpha-adrenergic agonist oxymetazoline (8) binds with high affinity at calf brain 5-HT1D rece... |