盐酸羟甲唑啉
一般危化品
盐酸羟甲唑啉结构式
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常用名 | 盐酸羟甲唑啉 | 英文名 | Oxymetazoline hydrochloride |
|---|---|---|---|---|
| CAS号 | 2315-02-8 | 分子量 | 296.836 | |
| 密度 | 1.08g/cm3 | 沸点 | 431.9ºC at 760mmHg | |
| 分子式 | C16H25ClN2O | 熔点 | >270°C (分解) | |
| MSDS | 中文版 美版 | 闪点 | 215ºC | |
| 符号 |
GHS06 |
信号词 | Danger |
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Cilazapril stability in the presence of hydrochlorothiazide in model mixtures and fixed dose combination.
Acta Pol. Pharm. 70(6) , 1079-85, (2013) The presented study aimed at the evaluation of hydrochlorothiazide influence on cilazapril stability in model mixture and fixed dose tablet formulation. The degradation of cilazapril in the presence of hydrochlorothiazide took place according to autocatalytic... |
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Selectivity of the imidazoline alpha-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned alpha 1-adrenoceptor subtypes.
Br. J. Pharmacol. 116 , 1611, (1995) 1. To investigate the structure-activity relationships of alpha-adrenoceptor agonists for the alpha 1-adrenoceptor subtypes, we have compared the imidazoline class of compounds, oxymetazoline and cirazoline, with the phenethylamine, noradrenaline, in their af... |
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Interaction of the alpha-adrenoceptor agonist oxymetazoline with serotonin 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors.
Eur. J. Pharmacol. 196 , 213, (1991) Oxymetazoline was recognized with nanomolar affinity by 5-HT1A, 5-HT1B and 5-HT1D binding sites and mimicked the effects of 5-hydroxytryptamine with about the same potency and intrinsic activity as the endogenous amine in the corresponding functional tests. A... |
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Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation.
J. Med. Chem. 41 , 2243-2251, (1998) Benzylimidazolines may represent a class of 5-HT1D ligands that has yet to be exploited. On the basis of a previous report that the 2-(substituted-benzyl)imidazoline alpha-adrenergic agonist oxymetazoline (8) binds with high affinity at calf brain 5-HT1D rece... |