Succinohydrazide
Succinohydrazide structure
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Common Name | Succinohydrazide | ||
|---|---|---|---|---|
| CAS Number | 4146-43-4 | Molecular Weight | 146.148 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 540.2±33.0 °C at 760 mmHg | |
| Molecular Formula | C4H10N4O2 | Melting Point | 170-171 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 280.5±25.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Efficient Delivery of DOX to Nuclei of Hepatic Carcinoma Cells in the Subcutaneous Tumor Model Using pH-Sensitive Pullulan-DOX Conjugates.
ACS Appl. Mater. Interfaces 7 , 15855-65, (2015) A series of pullulan-doxorubicin conjugates (Pu-DOXs) were investigated for effectively delivering DOX to nuclei of hepatic carcinoma cells in subcutaneous tumor model. These Pu-DOXs were prepared by conjugating DOX onto pullulan molecule via pH-responsive hy... |
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Pharmacokinetics and biodistribution of 99mTc N-MPO in healthy human volunteers.
Clin. Nucl. Med. 39(1) , e14-9, (2013) Tc N-MPO ([Tc N(MPO)(PNP5)]: HMPO = 2-mercaptopyridine N-oxide, and PNP5 = N-ethoxyethyl-N,N-bis[2-(bis(3-methoxypropyl)phosphino)ethyl]amine) is a new Tc radiotracer useful for myocardial perfusion imaging. This study was designed to determine its pharmacoki... |
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Biodistribution of nanostructured lipid carriers: a tomographic study.
Eur. J. Pharm. Biopharm. 89 , 145-56, (2015) This study describes the preparation, characterization, and biodistribution of radiolabelled nanostructured lipid carriers (NLCs) especially designed for in vivo tomographic study. A preliminary formulative study was conducted in order to incorporate (99m)Tc ... |
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Microscale synthesis of dextran-based multivalent N-linked oligosaccharide probes.
Anal. Biochem. 277(1) , 127-34, (2000) We developed a convenient method for the synthesis of dextran-based multivalent probes containing N-linked oligosaccharides which is efficient even in a small scale. Oligosaccharides were derivatized with succinic dihydrazide and dimethylamine borane under a ... |
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[Modification of DNA with dihydrazide of succinic acid for preparation of hybridization probes].
Bioorg. Khim. 15(10) , 1341-5, (1989) A two-step chemical method of introduction of nonradioactive labels in DNA was proposed. At first step DNA is modified by succinic dihydrazide at pH 5.0 and 95 degrees C, or at pH 4.5 and 37 degrees C in presence of sodium bisulfite. Then FITC or biotin are j... |
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DNA or RNA oligonucleotide 2'-hydrazides for chemoselective click-type ligation with carbonyl compounds.
Nucleosides Nucleotides Nucleic Acids 30(7-8) , 577-84, (2011) An efficient method for the synthesis of DNA or RNA oligonucleotide 2'-hydrazides is described. Fully deprotected oligonucleotides containing a hydrazide group at the 2'-position of a uridine residue were obtained by a novel two-step procedure: periodate clea... |