Succinohydrazide

Modify Date: 2025-08-20 17:09:34

Succinohydrazide Structure
Succinohydrazide structure
 Common Name Succinohydrazide
CAS Number 4146-43-4 Molecular Weight 146.148
Density 1.3±0.1 g/cm3 Boiling Point 540.2±33.0 °C at 760 mmHg
Molecular Formula C4H10N4O2 Melting Point 170-171 °C(lit.)
MSDS Chinese USA Flash Point 280.5±25.4 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Names

Name Butanedihydrazide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 540.2±33.0 °C at 760 mmHg
Melting Point 170-171 °C(lit.)
Molecular Formula C4H10N4O2
Molecular Weight 146.148
Flash Point 280.5±25.4 °C
Exact Mass 146.080383
PSA 110.24000
LogP -3.18
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.526

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WM7500000
CHEMICAL NAME :
Succinic acid, dihydrazide
CAS REGISTRY NUMBER :
4146-43-4
BEILSTEIN REFERENCE NO. :
1775110
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C4-H10-N4-O2
MOLECULAR WEIGHT :
146.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 4,259,1961

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS WM7500000
HS Code 2928000090

 Synthetic Route

Dimethyl succinate structure

Dimethyl succinate

CAS#:106-65-0

~93%

Succinohydrazide Structure

Succinohydrazide

CAS#:4146-43-4

Literature: Synthesis, , # 3 p. 287 - 289
Diethyl succinate structure

Diethyl succinate

CAS#:123-25-1

~%

Succinohydrazide Structure

Succinohydrazide

CAS#:4146-43-4

Literature: Chemische Berichte, , vol. 39, p. 3375
Succinic anhydride structure

Succinic anhydride

CAS#:108-30-5

~%

Succinohydrazide Structure

Succinohydrazide

CAS#:4146-43-4

Literature: Journal of the American Chemical Society, , vol. 73, p. 4716,4717
2,2'-ethanediylidene-bis-oxazolidine-4,5-dione structure

2,2'-ethanediyl...

CAS#:17511-68-1

~%

Succinohydrazide Structure

Succinohydrazide

CAS#:4146-43-4

Literature: Tetrahedron, , vol. 24, p. 2583 - 2590
Succinimide structure

Succinimide

CAS#:123-56-8

~%

Succinohydrazide Structure

Succinohydrazide

CAS#:4146-43-4

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2>92, p. 102
Succinic acid structure

Succinic acid

CAS#:110-15-6

~%

Succinohydrazide Structure

Succinohydrazide

CAS#:4146-43-4

Literature: Journal of the Chemical Society [Section] C: Organic, , p. 2629 - 2631
ethane-1,1,2,2-tetracarboxylic acid tetrahydrazide structure

ethane-1,1,2,2-...

CAS#:24820-65-3

Water structure

Water

CAS#:7732-18-5

~%

Succinohydrazide Structure

Succinohydrazide

CAS#:4146-43-4

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2>94, p. 279,370,381
Ethanol structure

Ethanol

CAS#:64-17-5

Hydrazine hydrate structure

Hydrazine hydrate

CAS#:7803-57-8

Diethyl succinate structure

Diethyl succinate

CAS#:123-25-1

~%

Succinohydrazide Structure

Succinohydrazide

CAS#:4146-43-4

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2>92, p. 102
2,5-Pyrrolidinedione,1-amino- structure

2,5-Pyrrolidine...

CAS#:19283-13-7

Hydrazine hydrate structure

Hydrazine hydrate

CAS#:7803-57-8

~%

Succinohydrazide Structure

Succinohydrazide

CAS#:4146-43-4

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2>92, p. 102

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles6

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A series of pullulan-doxorubicin conjugates (Pu-DOXs) were investigated for effectively delivering DOX to nuclei of hepatic carcinoma cells in subcutaneous tumor model. These Pu-DOXs were prepared by ...

Pharmacokinetics and biodistribution of 99mTc N-MPO in healthy human volunteers.

Clin. Nucl. Med. 39(1) , e14-9, (2013)

Tc N-MPO ([Tc N(MPO)(PNP5)]: HMPO = 2-mercaptopyridine N-oxide, and PNP5 = N-ethoxyethyl-N,N-bis[2-(bis(3-methoxypropyl)phosphino)ethyl]amine) is a new Tc radiotracer useful for myocardial perfusion i...

Biodistribution of nanostructured lipid carriers: a tomographic study.

Eur. J. Pharm. Biopharm. 89 , 145-56, (2015)

This study describes the preparation, characterization, and biodistribution of radiolabelled nanostructured lipid carriers (NLCs) especially designed for in vivo tomographic study. A preliminary formu...

 Synonyms

succinic acid hydrazide
Succinic acid,dihydrazide
Succinic hydrazide
Succinic Dihydrazide
Butanedioic acid, dihydrazide
Succinyl dihydrazide
MFCD00007613
Succinohydrazide
Butanedioic acid,dihydrazide
Succinhydrazide
Succinoyldihydrazine
Butanediohydrazide
EINECS 223-970-9
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