Succinohydrazide
Names
[ CAS No. ]:
4146-43-4
[ Name ]:
Succinohydrazide
[Synonym ]:
succinic acid hydrazide
Succinic acid,dihydrazide
Succinic hydrazide
Succinic Dihydrazide
Butanedioic acid, dihydrazide
Succinyl dihydrazide
MFCD00007613
Succinohydrazide
Butanedioic acid,dihydrazide
Succinhydrazide
Succinoyldihydrazine
Butanediohydrazide
EINECS 223-970-9
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
540.2±33.0 °C at 760 mmHg
[ Melting Point ]:
170-171 °C(lit.)
[ Molecular Formula ]:
C4H10N4O2
[ Molecular Weight ]:
146.148
[ Flash Point ]:
280.5±25.4 °C
[ Exact Mass ]:
146.080383
[ PSA ]:
110.24000
[ LogP ]:
-3.18
[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C
[ Index of Refraction ]:
1.526
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WM7500000
- CHEMICAL NAME :
- Succinic acid, dihydrazide
- CAS REGISTRY NUMBER :
- 4146-43-4
- BEILSTEIN REFERENCE NO. :
- 1775110
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C4-H10-N4-O2
- MOLECULAR WEIGHT :
- 146.18
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 4,259,1961
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
WM7500000
[ HS Code ]:
2928000090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2928000090
[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
Articles
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A series of pullulan-doxorubicin conjugates (Pu-DOXs) were investigated for effectively delivering DOX to nuclei of hepatic carcinoma cells in subcutaneous tumor model. These Pu-DOXs were prepared by ...
Pharmacokinetics and biodistribution of 99mTc N-MPO in healthy human volunteers.Clin. Nucl. Med. 39(1) , e14-9, (2013)
Tc N-MPO ([Tc N(MPO)(PNP5)]: HMPO = 2-mercaptopyridine N-oxide, and PNP5 = N-ethoxyethyl-N,N-bis[2-(bis(3-methoxypropyl)phosphino)ethyl]amine) is a new Tc radiotracer useful for myocardial perfusion i...
Biodistribution of nanostructured lipid carriers: a tomographic study.Eur. J. Pharm. Biopharm. 89 , 145-56, (2015)
This study describes the preparation, characterization, and biodistribution of radiolabelled nanostructured lipid carriers (NLCs) especially designed for in vivo tomographic study. A preliminary formu...