hydroflumethiazide
hydroflumethiazide structure
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Common Name | hydroflumethiazide | ||
|---|---|---|---|---|
| CAS Number | 135-09-1 | Molecular Weight | 331.29200 | |
| Density | 1.678g/cm3 | Boiling Point | 531.6ºC at 760 mmHg | |
| Molecular Formula | C8H8F3N3O4S2 | Melting Point | 272-273ºC | |
| MSDS | Chinese USA | Flash Point | 275.3ºC | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Do thiazides reduce intestinal oxalate absorption?: a study in vitro using rabbit colon.
Clin. Sci. 86(3) , 353-7, (1994) 1. The purpose of the present study was to examine the effects of various diuretics on intestinal oxalate transport. Transmural oxalate fluxes were measured across isolated, short-circuited tissue segments removed from rabbits and placed in Ussing chambers. 2... |
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Comparative effects of LN 5330 and diazoxide on insulin release and 86Rb+ permeability in perifused rat islets of Langerhans.
Biochem. Pharmacol. 42(4) , 787-91, (1991) The benzothiadiazine derivative LN 5330 (chloro-7 trifluoromethyl-6 benzothiadiazine-1,2,4-dioxide-1,1) has been shown to inhibit insulin secretion and calcium uptake. The present study was carried out to investigate the effects of LN 5330 on insulin release ... |
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Metabolic effects of propranolol and hydroflumethiazide treatment in Kenyans with mild to moderate essential hypertension.
East Afr. Med. J. 70(11) , 696-700, (1993) In a prospective single-blind comparative trial, sixty newly diagnosed mild to moderate hypertensives were randomly assigned to either propranolol or hydroflumethiazide monotherapy. Baseline fasting serum glucose lipid profiles, serum uric acid and potassium ... |
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Photoaugmentation effects demonstrated in vitro.
Photodermatol. Photoimmunol. Photomed. 12(6) , 227-32, (1996) A number of sulphonamide-derived oral antidiabetics and diuretics were investigated for phototoxic properties, using different sources of light, by means of a photohemolysis test. Photohemolysis was obtained after irradiation with UVA, visible light and solar... |
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Phototoxicity to sulphonamide-derived oral antidiabetics and diuretics: investigations in hairless mice.
Photodermatol. Photoimmunol. Photomed. 13(1-2) , 4-8, (1997) The oral antidiabetics glibenclamide, glipizide, glymidine, tolazamide and tolbutamide and the diuretics bemetizide, bendroflumethiazide, benzylhydrochlorothiazide, bumetanide, butizide, furosemide, hydrochlorothiazide, hydroflumethiazide and trichlormethiazi... |
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Rapid determination of losartan and losartan acid in human plasma by multiplexed LC-MS/MS.
J. Sep. Sci. 32(20) , 3388-94, (2009) A rapid LC-MS/MS method has been developed and validated for the determination of losartan (LOS) and its metabolite losartan acid (LA) (EXP-3174) in human plasma using multiplexing technique (two HPLC units connected to one MS/MS). LOS and LA were extracted f... |
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Spectrophotometric determination of hydroflumethiazide.
J. Pharm. Biomed. Anal. 7(6) , 759-63, (1989)
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A modified residual method to estimate the zero-order absorption rate constant in a one-compartment model.
Biopharm. Drug Dispos. 18(2) , 93-101, (1997) The objective of this work was to develop a simple residual method to estimate the rate constant for actual or apparent zero-order absorption into a one-compartment model. The method is based on the fact that, in theory, a plot of residuals versus e-Kt is lin... |
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Randomised double-blind comparative study of efficacy and safety of hydroflumethiazide and reserpine and chlortalidone and atenolol in the treatment of mild to moderate hypertension in black patients.
J. Hum. Hypertens. 7(5) , 447-50, (1993) This randomised, double-blind study compared the efficacy and safety of a fixed combination of hydroflumethiazide 50 mg and reserpine 0.125 mg (H-R) and chlortalidone 12.5 mg and atenolol 50 mg (C-A) in adult black patients with mild to moderate hypertension ... |
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Parodoxical rise in urinary albumin levels after treatment of essential hypertension.
S. Afr. Med. J. 87(9) , 1147-8, (1997)
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