N-Boc-Ethylenediamine

N-Boc-Ethylenediamine Structure
N-Boc-Ethylenediamine structure
Common Name N-Boc-Ethylenediamine
CAS Number 57260-73-8 Molecular Weight 160.214
Density 1.0±0.1 g/cm3 Boiling Point 252.8±23.0 °C at 760 mmHg
Molecular Formula C7H16N2O2 Melting Point N/A
MSDS Chinese USA Flash Point 106.7±22.6 °C
Symbol GHS05
GHS05
Signal Word Danger

Synthesis and antitumor properties of an anthraquinone bisubstituted by the copper chelating peptide Gly-Gly-L-His.

J. Med. Chem. 36 , 2084, (1993)

A new molecule 4 [(GGH-DAE)2DHQ] associating the 1,4,5,8-tetrahydroxyanthraquinone ring (DHQ) of the antitumor drug mitoxantrone (2), two diaminoethylene chains (DAE), and the metal-chelating peptide Gly-Gly-His (GGH) has been synthesized. Such a molecule pre...

A convenient and scalable synthesis of ethyl N-[(2-Boc-amino)ethyl]glycinate and its hydrochloride. Key intermediates for peptide nucleic acid synthesis.

J. Org. Chem. 68 , 1630, (2003)

An improved synthesis of ethyl N-[(2-Boc-amino)ethyl]glycinate and its hydrochloride salt is reported. The synthesis is based on the reductive alkylation of Boc-ethylenediamine with ethyl glyoxylate hydrate and furnishes the title compound in near quantitativ...

Synthesis and evaluation of some nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups as novel hypoxic cell selective cytotoxic agents.

J. Med. Chem. 34 , 3132, (1991)

Basic nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups were prepared and evaluated as novel hypoxic cell selective cytotoxic agents. In vitro, N-(2-aminoethyl)-N-methyl-3-nitro-4-(1-methyl-1-nitroethyl)benzene sulfonamide hydroc...

Synthesis of N,N-dilactitol ethylenediamine: a versatile spacer for attachment of residualizing labels to protein.

Anal. Biochem. 205 , 369, (1992)

Design and evaluation of a novel trifluorinated imaging agent for assessment of bile acid transport using fluorine magnetic resonance imaging.

J. Pharm. Sci. 103(11) , 3782-92, (2014)

Previously, we developed a trifluorinated bile acid, CA-lys-TFA, with the objective of noninvasively assessing bile acid transport in vivo using (19) F magnetic resonance imaging (MRI). CA-lys-TFA was successfully imaged in the mouse gallbladder, but was susc...

G. Kada et al.

Biochim. Biophys. Acta 1427 , 33, (1998)