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57260-73-8

57260-73-8 structure
57260-73-8 structure
  • Name: N-Boc-Ethylenediamine
  • Chemical Name: N-Boc-Ethylenediamine
  • CAS Number: 57260-73-8
  • Molecular Formula: C7H16N2O2
  • Molecular Weight: 160.214
  • Catalog: Organic raw materials Amino compound Acyclic monoamines, polyamines and their derivatives and salts
  • Create Date: 2018-06-22 17:22:08
  • Modify Date: 2024-01-02 18:25:40
  • PROTAC Linker 22 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 22 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name N-Boc-Ethylenediamine
Synonyms Carbamic acid, N-(2-aminoethyl)-, 1,1-dimethylethyl ester
N-tert-Boc-ethylenediamine
tert-butyl-(2-aminoethyl)carbamat
tert-butyl (2-aminoethyl)carbamate
2-Methyl-2-propanyl (2-aminoethyl)carbamate
tert-butyl N-(2-aminoethyl)carbamate
MFCD00191871
N-(tert-Butoxycarbonyl)-1,2-diaminoethane
Description PROTAC Linker 22 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 22 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl-Chain

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.0±0.1 g/cm3
Boiling Point 252.8±23.0 °C at 760 mmHg
Molecular Formula C7H16N2O2
Molecular Weight 160.214
Flash Point 106.7±22.6 °C
Exact Mass 160.121185
PSA 64.35000
LogP 0.54
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.454
Storage condition Refrigerator (+4°C)
Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2735 8/PG 3
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 2924199090
HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%