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117499-16-8

117499-16-8 structure
117499-16-8 structure
  • Name: 1,7-Bis-Boc-1,4,7-triazaheptane
  • Chemical Name: tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]ethyl]carbamate
  • CAS Number: 117499-16-8
  • Molecular Formula: C14H29N3O4
  • Molecular Weight: 303.39800
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-06-20 01:55:44
  • Modify Date: 2025-08-22 09:44:46
  • 1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Name tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]ethyl]carbamate
Synonyms 1,7-Bis-Boc-1,4,7-triazaheptane
Bis(2-Methyl-2-Propanyl) (Iminodi-2,1-Ethanediyl)Biscarbamate
Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate
Description 1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Density 1.0±0.1g/cm3
Boiling Point 440.5±30.0°C at 760 mmHg
Molecular Formula C14H29N3O4
Molecular Weight 303.39800
Flash Point 220.2±24.6°C
Exact Mass 303.21600
PSA 88.69000
LogP 2.79810
Index of Refraction 1.466
Storage condition 2-8°C
Hazard Codes Xi
HS Code 2924199090
HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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title: CAS No. 117499-16-8 | Chemsrc address: https://www.chemsrc.com/en/baike/129684.html

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