N-Boc-Ethylenediamine

Modify Date: 2025-08-23 11:44:37

N-Boc-Ethylenediamine Structure
N-Boc-Ethylenediamine structure
 Common Name N-Boc-Ethylenediamine
CAS Number 57260-73-8 Molecular Weight 160.214
Density 1.0±0.1 g/cm3 Boiling Point 252.8±23.0 °C at 760 mmHg
Molecular Formula C7H16N2O2 Melting Point N/A
MSDS Chinese USA Flash Point 106.7±22.6 °C
Symbol GHS05
GHS05		 Signal Word Danger

 Use of N-Boc-Ethylenediamine


PROTAC Linker 22 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 22 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name N-Boc-Ethylenediamine
Synonym More Synonyms

 N-Boc-Ethylenediamine Biological Activity

Description PROTAC Linker 22 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 22 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl-Chain

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 252.8±23.0 °C at 760 mmHg
Molecular Formula C7H16N2O2
Molecular Weight 160.214
Flash Point 106.7±22.6 °C
Exact Mass 160.121185
PSA 64.35000
LogP 0.54
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.454
InChIKey AOCSUUGBCMTKJH-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)NCCN
Storage condition Refrigerator (+4°C)

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2735 8/PG 3
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 2924199090

 Synthetic Route

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles6

More Articles
Synthesis and antitumor properties of an anthraquinone bisubstituted by the copper chelating peptide Gly-Gly-L-His.

J. Med. Chem. 36 , 2084, (1993)

A new molecule 4 [(GGH-DAE)2DHQ] associating the 1,4,5,8-tetrahydroxyanthraquinone ring (DHQ) of the antitumor drug mitoxantrone (2), two diaminoethylene chains (DAE), and the metal-chelating peptide ...

A convenient and scalable synthesis of ethyl N-[(2-Boc-amino)ethyl]glycinate and its hydrochloride. Key intermediates for peptide nucleic acid synthesis.

J. Org. Chem. 68 , 1630, (2003)

An improved synthesis of ethyl N-[(2-Boc-amino)ethyl]glycinate and its hydrochloride salt is reported. The synthesis is based on the reductive alkylation of Boc-ethylenediamine with ethyl glyoxylate h...

Synthesis and evaluation of some nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups as novel hypoxic cell selective cytotoxic agents.

J. Med. Chem. 34 , 3132, (1991)

Basic nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups were prepared and evaluated as novel hypoxic cell selective cytotoxic agents. In vitro, N-(2-aminoethyl)-N-methyl-...

 Synonyms

Carbamic acid, N-(2-aminoethyl)-, 1,1-dimethylethyl ester
N-tert-Boc-ethylenediamine
tert-butyl-(2-aminoethyl)carbamat
tert-butyl (2-aminoethyl)carbamate
2-Methyl-2-propanyl (2-aminoethyl)carbamate
tert-butyl N-(2-aminoethyl)carbamate
MFCD00191871
N-(tert-Butoxycarbonyl)-1,2-diaminoethane
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Chemsrc provides N-Boc-Ethylenediamine(CAS#:57260-73-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of N-Boc-Ethylenediamine are included as well.>> amp version: N-Boc-Ethylenediamine

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