9,10-Dimethylanthracene

9,10-Dimethylanthracene Structure
9,10-Dimethylanthracene structure
Common Name 9,10-Dimethylanthracene
CAS Number 781-43-1 Molecular Weight 206.28200
Density 1.084g/cm3 Boiling Point 370.8ºC at 760 mmHg
Molecular Formula C16H14 Melting Point 182-184 °C(lit.)
MSDS Chinese USA Flash Point 169.1ºC
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.

Eur. J. Med. Chem. 43 , 714-40, (2008)

Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and organic compounds of different classes by optimal descriptors....

Antioxidant-photosensitizer dual-loaded polymeric micelles with controllable production of reactive oxygen species.

Int. J. Pharm. 471(1-2) , 339-48, (2014)

Poly(ethylene glycol)-b-poly(caprolactone) (PEG-b-PCL) micelles dually loaded with both pheophorbide a (PhA) as a photosensitizer and β-carotene (CAR) as a singlet oxygen ((1)O2) scavenger were designed to control photodynamic therapy (PDT) activity in cancer...

Determination of descriptors for polycyclic aromatic hydrocarbons and related compounds by chromatographic methods and liquid-liquid partition in totally organic biphasic systems.

J. Chromatogr. A. 1361 , 240-54, (2014)

Retention factors on several columns and at various temperatures using gas chromatography and from reversed-phase liquid chromatography on a SunFire C18 column with various mobile phase compositions containing acetonitrile, methanol and tetrahydrofuran as str...

Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test.

Mutat. Res. 290(2) , 175-82, (1993)

Drosophila melanogaster stock consisting of meiotic recombination deficient (Rec-) double mutant mei-9a mei-41D5 males and Rec+ females was exposed at the larval stage to an aromatic amine or a polycyclic aromatic hydrocarbon. After emergence as adult flies, ...

Immunomodulatory effects of dietary exposure to selected polycyclic aromatic hydrocarbons in the bluegill (Lepomis macrochirus).

Int. J. Toxicol. 29(5) , 532-45, (2010)

Polycyclic aromatic hydrocarbons (PAH) have been demonstrated to affect immune system modulation. The freshwater species of fish, Lepomis macrochirus (bluegill), was employed to investigate the effects of a 14-day dietary exposure to PAH including 2-aminoanth...

In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.

Proc. Natl. Acad. Sci. U. S. A. 105 , 9059-64, (2008)

The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have implemented an efficient and robust high-throughput cell-based screen (1,536-well format) based on p...

Stereoselective fungal metabolism of methylated anthracenes.

Appl. Environ. Microbiol. 56(3) , 661-8, (1990)

The metabolism of 9-methylanthracene (9-MA), 9-hydroxymethylanthracene (9-OHMA), and 9,10-dimethylanthracene (9,10-DMA) by the fungus Cunninghamella elegans ATCC 36112 is described. The metabolites were isolated by high-performance liquid chromatography and c...

Singlet oxygen generation by porphyrins and the kinetics of 9,10-dimethylanthracene photosensitization in liposomes.

Photochem. Photobiol. 57(5) , 808-13, (1993)

Two new sensitizers are introduced for a potential use in photodynamic therapy: Zn(2+)- and MG(2+)-tetrabenzoporphyrin (ZnTBP and MgTBP). A comparative study of the quantum yields of singlet oxygen generation (phi delta) of hematoporphyrin derivative (HpD), P...

Pulmonary carcinogenesis in mice with a single intratracheal instillation of 9, 10-dimethyl benz[a]anthracene.

Drug Chem. Toxicol. 31(4) , 459-71, (2008)

A single intratracheal instillation of 9,10-dimethyl benz(a)anthracene (DMBA) at 3 different doses of 5, 10, and 20 mg/kg body weight to Balb/c mice for 12 weeks had caused a significant incidence of pulmonary tumors along with inflammatory changes. The numbe...

Liposome binding constants and singlet oxygen quantum yields of hypericin, tetrahydroxy helianthrone and their derivatives: studies in organic solutions and in liposomes.

J. Photochem. Photobiol. B, Biol. 57(2-3) , 149-58, (2000)

The spectroscopy and photophysics of several hypericin and helianthrone derivatives were studied in methanol and when bound to liposomes. The singlet oxygen quantum yields (phi(delta)) were measured indirectly relative to Rose Bengal and hematoporphyrin IX, e...