methocarbamol
methocarbamol structure
|
Common Name | methocarbamol | ||
|---|---|---|---|---|
| CAS Number | 532-03-6 | Molecular Weight | 241.240 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 472.5±40.0 °C at 760 mmHg | |
| Molecular Formula | C11H15NO5 | Melting Point | 95-97ºC | |
| MSDS | Chinese USA | Flash Point | 239.6±27.3 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
|
A new HPLC technique for the separation of methocarbamol enantiomers.
J. Pharm. Pharmacol. 51(7) , 873-5, (1999) We have developed a stereoselective high-performance liquid chromatography technique for analytical separation of methocarbamol enantiomers. Precolumn derivatization was performed at room temperature using (-)-menthylchloroformate as a chiral reagent in the p... |
|
|
Spectrofluorometric determination of methocarbamol in pharmaceutical preparations and human plasma.
J. Fluoresc. 21(2) , 555-61, (2011) A simple, sensitive and rapid spectrofluorometric method for determination of methocarbamol in pharmaceutical formulations and spiked human plasma has been developed. The proposed method is based on the measurement of the native fluorescence of methocarbamol ... |
|
|
A stability-indicating high-performance liquid chromatographic method for the determination of methocarbamol in veterinary preparations.
J. AOAC Int. 92(5) , 1602-5, (2009) An isocratic HPLC method was developed and validated for the quantitation of methocarbamol in the presence of its degradation products. Quantitation was achieved using a reversed-phase C18 column at ambient temperature with mobile phase consisting of methanol... |
|
|
Efficacy and safety of sodium hyaluronate in the treatment of Wilkes stage II disease.
J. Oral Maxillofac. Surg. 66(11) , 2243-6, (2008) To show whether an intra-articular (IA) infiltration of 1 mL sodium hyaluronate (SH) into the temporomandibular joint (TMJ) would significantly reduce pain and improve joint function in Wilkes stage II disease, compared with the oral administration of a combi... |
|
|
Simultaneous spectrophotometric determination of diclofenac potassium and methocarbamol in binary mixture using chemometric techniques and artificial neural networks.
Drug Test. Anal. 3(4) , 228-33, (2011) In this study, the simultaneous determination of diclofenac potassium (DP) and methocarbamol (MT) by chemometric approaches and artificial neural networks using UV spectrophotometry has been reported as a simple alternative to using separate models for each c... |
|
|
Effect of preoperative intravenous methocarbamol and intravenous acetaminophen on opioid use after primary total hip and knee replacement.
Orthopedics 36(2 Suppl) , 25-32, (2013) Between 2010 and 2011, a perioperative pain protocol for primary total hip and knee replacement at one Florida medical center replaced preoperative oral analgesics with intravenous methocarbamol and intravenous acetaminophen. This is a retrospective cohort st... |
|
|
Bioequivalence study with two different oral formulations of methocarbamol in healthy subjects. A mono-centre, comparative, randomized, open-label, single-dose, 2-way crossover study.
Arzneimittelforschung 59(5) , 238-42, (2009) The objective of this study was to compare the pharmacokinetic profile of a new oral methocarbamol (CAS 532-03-6) formulation (DoloVisano Methocarbamol 750 mg Tabletten) to that of a registered reference product and to demonstrate the bioequivalence of the fo... |
|
|
Strychnine poisoning: gone but not forgotten.
Emerg. Med. J. 28(1) , 84, (2011) Strychnine was used as a pesticide until 1968 and a rodenticide until 2006 when its sale was banned throughout the EU and all supplies recalled. A case of strychnine poisoning seen in a UK emergency department in 2009 is reported to remind clinicians of the f... |
|
|
50 Years Ago in CORR: A clinical study of 46 males with low-back disorders treated with Methocarbamol. Andres Grisolia MD and J.E.M. Thomson CORR 1959;13:299-304.
Clin. Orthop. Relat. Res. 467(10) , 2752-4, (2009)
|
|
|
Seizure-like behavior in cats.
Can. Vet. J. 43(1) , 3, (2002)
|