Prunetin

Prunetin Structure
Prunetin structure
Common Name Prunetin
CAS Number 552-59-0 Molecular Weight 284.263
Density 1.4±0.1 g/cm3 Boiling Point 546.5±50.0 °C at 760 mmHg
Molecular Formula C16H12O5 Melting Point 240-242ºC
MSDS Chinese USA Flash Point 209.7±23.6 °C

Preparation and evaluation of surface-bonded tricationic ionic liquid silica as stationary phases for high-performance liquid chromatography.

J. Chromatogr. A. 1396 , 62-71, (2015)

Two tricationic ionic liquids were prepared and then bonded onto the surface of supporting silica materials through "thiol-ene" click chemistry as new stationary phases for high-performance liquid chromatography. The obtained columns of tricationic ionic liqu...

Absorption of red clover isoflavones in human subjects: results from a pilot study.

Br. J. Nutr. 103(11) , 1569-72, (2010)

In addition to soya-derived preparations, red clover-based dietary supplements have gained considerable interest as an alternative isoflavone (IF) source. While metabolism and bioavailability of the main IF from both sources have already been investigated, st...

The phytoestrogen prunetin affects body composition and improves fitness and lifespan in male Drosophila melanogaster.

FASEB J. 30 , 948-58, (2016)

Dietary isoflavones, a group of secondary plant compounds that exhibit phytoestrogenic properties, are primarily found in soy. Prunetin, a representative isoflavone, was recently found to affect cell signaling in cultured cells; however, in vivo effects remai...

Dalsympathetin--a new isoflavone gentiobioside from Dalbergia sympathetica (Dennst.).

Nat. Prod. Res. 20(2) , 195-200, (2006)

Two isoflavonoids isolated from Dalbergia sympathetica were identified as 5,4'-dihydroxy-7-methoxyisoflavone (1) (Prunetin) and Prunetin-4'-O-beta-D-gentiobioside (2) (Dalsympathetin). The natural occurrence of Dalsympathetin is reported for the first time. T...

Effects of prunetin on the proteolytic activity, secretion and gene expression of MMP-3 in vitro and production of MMP-3 in vivo.

Korean J. Physiol. Pharmacol. 20 , 221-8, (2016)

We investigated whether prunetin affects the proteolytic activity, secretion, and gene expression of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the rat knee joint to evaluate...

[Studies on chemical constituents of Primula sikkmensis].

Zhong Yao Cai 31(1) , 44-6, (2008)

To study the chemical constituents of Primula sikkmensis Hook.The chemical constituents of the plant were isolated and purified by column chromatography and their structures were elucidated by spectroscopic analysis.Seven compounds were isolated and identifie...

A synthesis of prunetin.

Curr. Sci. 18(11) , 404-6, (1949)

Molecular mechanisms underlying the anti-obesity potential of prunetin, an O-methylated isoflavone.

Biochem. Pharmacol. 85(10) , 1525-33, (2013)

Prunetin is an O-methylated isoflavone, which is a type of flavonoid. There are a limited number of reports detailing the biological activities of prunetin. Although an anti-inflammatory effect of prunetin has been reported in vitro, to our knowledge, there h...

Secondary metabolites from the roots of Neolitsea daibuensis and their anti-inflammatory activity.

J. Nat. Prod. 74(12) , 2489-96, (2011)

Bioassay-guided fractionation of the roots of Neolitsea daibuensis afforded three new β-carboline alkaloids, daibucarbolines A-C (1-3), three new sesquiterpenoids, daibulactones A and B (4 and 5) and daibuoxide (6), and 20 known compounds. The structures of 1...

Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry.

Rapid Commun. Mass Spectrom. 17(12) , 1256-64, (2003)

In an international context of promoting scientific research on food safety, the interest in molecules having potential hormonal disrupting effects is growing. While industrial endocrine disruptors (phthalates, alkylphenols, PCBs, etc.) have been studied for ...