p-chloromercuribenzoic acid
p-chloromercuribenzoic acid structure
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Common Name | p-chloromercuribenzoic acid | ||
|---|---|---|---|---|
| CAS Number | 59-85-8 | Molecular Weight | 357.15600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H5ClHgO2 | Melting Point | 287 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS06, GHS08, GHS09 |
Signal Word | Danger | |
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Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nat. Chem. Biol. 5 , 765-71, (2009) Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279... |
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Reinvestigation of drugs and chemicals as aquaporin-1 inhibitors using pressure-induced hemolysis in human erythrocytes.
Biol. Pharm. Bull. 35(11) , 2088-91, (2012) Recently, we have found that pressure-induced hemolysis is enhanced by inhibiting water transport via aquaporin-1 (AQP1), as seen in p-chloromercuribenzoate (pCMB)-treated erythrocytes. So, using this method we reinvestigated the functions as AQP1 inhibitors ... |
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Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
Antimicrob. Agents Chemother. 53 , 5279-83, (2009) In this study, application of a dual absorbance/fluorescence assay to a chemical library screen identified several previously unknown inhibitors of mycobacteria. In addition, growth conditions had a significant effect on the activity profile of the library. S... |
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Synthetic cannabimimetic agents metabolized by carboxylesterases.
Drug Test. Anal. 7 , 565-76, (2015) Synthetic cannabimimetic agents are a large group of diverse compounds which act as agonists at cannabinoid receptors. Since 2004, synthetic cannabinoids have been used recreationally, although several of the compounds have been shown to cause severe toxicity... |
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[Investigation of functional groups of Cryptococcus albidus alpha-L-rhamnosidase].
Mikrobiol. Z. 74(4) , 19-28, (2012) The effect of cations, anions and specific chemical reagents: 1-[3-(dimethylamino)propyl]-3-ethylcarbodimide methiodide, EDTA, o-phenantroline, dithiotreitol, L-cysteine, beta-mercaptoethanol, p-chlormercurybenzoate (p-ChMB), N-ethylmaleimide on the alpha-L-r... |
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Cultured ruminal epithelial cells express a large-conductance channel permeable to chloride, bicarbonate, and acetate.
Pflugers Arch. 457(5) , 1003-22, (2009) The absorption of short-chain fatty acids (SCFA) from the rumen requires efficient mechanisms for both apical uptake and basolateral extrusion. Previous studies suggest that the rumen expresses a basolateral chloride conductance that might be permeable to SCF... |
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Functional activity of a monocarboxylate transporter, MCT1, in the human retinal pigmented epithelium cell line, ARPE-19.
Mol. Pharm. 2(2) , 109-17, (2005) The purpose of this study was to identify and characterize the functional activity of monocarboxylic acid transporter 1 (MCT1) on the human retinal pigmented epithelium (RPE) cell line, ARPE-19, and to evaluate whether the cell line can function as an in vitr... |
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The role of monocarboxylate transporters in uptake of lactic acid in HeLa cells.
Int. J. Pharm. 325(1-2) , 48-54, (2006) This study was aimed to identify the monocarboxylate transporters (MCTs) in HeLa cells and to delineate their role in transportation of L-lactic acid. The functional role of MCTs in lactic acid transport was evaluated at various mucosal pHs (4.5-7.4) or in th... |
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Dietary pectin up-regulates monocaboxylate transporter 1 in the rat gastrointestinal tract.
Exp. Physiol. 94(4) , 422-33, (2009) This work was undertaken to study the effect of pectin feeding on the expression level, cellular localization and functional activity of monocarboxylate transporter 1 (MCT1) in the gastrointestinal tract of rats. The results indicated that MCT1 protein level ... |
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Simultaneous modulation of transport and metabolism of acyclovir prodrugs across rabbit cornea: An approach involving enzyme inhibitors.
Int. J. Pharm. 320(1-2) , 104-13, (2006) The aim of this study is to identify the class of enzymes responsible for the hydrolysis of amino acid and dipeptide prodrugs of acyclovir (ACV) and to modulate transport and metabolism of amino acid and dipeptide prodrugs of acyclovir by enzyme inhibitors ac... |