p-chloromercuribenzoic acid

Modify Date: 2024-01-06 13:08:52

p-chloromercuribenzoic acid Structure
p-chloromercuribenzoic acid structure
Common Name p-chloromercuribenzoic acid
CAS Number 59-85-8 Molecular Weight 357.15600
Density N/A Boiling Point N/A
Molecular Formula C7H5ClHgO2 Melting Point 287 °C (dec.)(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

 Names

Name p-chloromercuribenzoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Melting Point 287 °C (dec.)(lit.)
Molecular Formula C7H5ClHgO2
Molecular Weight 357.15600
Exact Mass 357.96800
PSA 37.30000
LogP 1.24640

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OV8050000
CHEMICAL NAME :
Mercury, (p-carboxyphenyl)chloro-
CAS REGISTRY NUMBER :
59-85-8
LAST UPDATED :
199712
DATA ITEMS CITED :
22
MOLECULAR FORMULA :
C7-H4-Cl-Hg-O2.H
MOLECULAR WEIGHT :
357.16
WISWESSER LINE NOTATION :
QVR D-HG-G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg(Hg)/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.05 mg(Hg)/m3 DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,22,1973 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.05 mg(Hg)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.05 mg(Hg)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-FINLAND:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-FRANCE:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-GERMANY:TWA 0.01 ppm (0.1 mg(Hg)/m3) JAN 1993 OEL-HUNGARY:TWA 0.02 mg(Hg)/m3;STEL 0.04 mg(Hg)/m3 JAN 1993 OEL-JAPAN:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-POLAND:TWA 0.01 mg(Hg)/m3 JAN 1993 OEL-RUSSIA:TWA 0.05 mg(Hg)/m3;STEL 0.01 mg(Hg)/m3 JAN 1993 OEL-SWEDEN:TWA 0.05 mg(Hg)/m3 JAN 1993 OEL-THAILAND:STEL 0.05 mg(Hg)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MERCURY, ARYL AND INORGANIC-air:CL 0.1 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

 Safety Information

Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H300 + H310 + H330-H373-H410
Precautionary Statements P260-P273-P280-P301 + P310 + P330-P302 + P352 + P310-P304 + P340 + P310
Hazard Codes T+,N
Risk Phrases R26/27/28;R33
Safety Phrases S13-S28-S36-S45-S60-S61
RIDADR UN 2025 6.1/PG 2
WGK Germany 3
RTECS OV8050000
Packaging Group II
Hazard Class 6.1(a)

 Precursor & DownStream

Precursor  0

DownStream  1

 Articles30

More Articles
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

Reinvestigation of drugs and chemicals as aquaporin-1 inhibitors using pressure-induced hemolysis in human erythrocytes.

Biol. Pharm. Bull. 35(11) , 2088-91, (2012)

Recently, we have found that pressure-induced hemolysis is enhanced by inhibiting water transport via aquaporin-1 (AQP1), as seen in p-chloromercuribenzoate (pCMB)-treated erythrocytes. So, using this...

Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.

Antimicrob. Agents Chemother. 53 , 5279-83, (2009)

In this study, application of a dual absorbance/fluorescence assay to a chemical library screen identified several previously unknown inhibitors of mycobacteria. In addition, growth conditions had a s...

 Synonyms

MFCD00002526
4-Carboxy-phenylquecksilber(1+),Chlorid
PARA-CHLOROMERCURIBENZOICACID
P-CMB
P-CHLOROMERCURIBENZOIC ACID
4-(chloromercuri) benzoic acid
p-Chlormercuribenzoic Acid
4-Chloromercurio-benzoesaeure
EINECS 200-442-6
p-(chloromercuri)-benzoicaci
p-chloromercury(II)benzoic acid
p-chloro-mercuricbenzoicacid
4-CHLOROMERCURIBENZOIC ACID
usafd-3
P-CMBA
4-carboxy-phenylmercury (1+),chloride