Glycochenodeoxycholic acid sodium

Glycochenodeoxycholic acid sodium Structure
Glycochenodeoxycholic acid sodium structure
Common Name Glycochenodeoxycholic acid sodium
CAS Number 16564-43-5 Molecular Weight 471.605
Density N/A Boiling Point 655.6ºC at 760mmHg
Molecular Formula C26H42NNaO5 Melting Point N/A
MSDS Chinese USA Flash Point 350.3ºC

Comprehensive comparison of cultivable norovirus surrogates in response to different inactivation and disinfection treatments.

Appl. Environ. Microbiol. 80(18) , 5743-51, (2014)

Human norovirus is the leading cause of epidemic and sporadic acute gastroenteritis. Since no cell culture method for human norovirus exists, cultivable surrogate viruses (CSV), including feline calicivirus (FCV), murine norovirus (MNV), porcine enteric calic...

Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans.

Drug Metab. Dispos. 43 , 851-63, (2015)

Inhibition of hepatic transporters such as organic anion transporting polypeptides (OATPs) 1B can cause drug-drug interactions (DDIs). Determining the impact of perpetrator drugs on the plasma exposure of endogenous substrates for OATP1B could be valuable to ...

Mechanisms of cholesterol and saturated fatty acid lowering by Quillaja saponaria extract, studied by in vitro digestion model.

Food Funct. 6 , 1319-30, (2015)

Quillaja saponin extracts are known to reduce plasma cholesterol levels in humans. Here we study the mechanism of this effect with Quillaja Dry saponin extract (QD). In vitro model of triglyceride lipolysis is used to quantify the effect of QD on the solubili...

Bile acids repress hypoxia-inducible factor 1 signaling and modulate the airway immune response.

Infect. Immun. 82(9) , 3531-41, (2014)

Gastroesophageal reflux (GER) frequently occurs in patients with respiratory disease and is particularly prevalent in patients with cystic fibrosis. GER is a condition in which the duodenogastric contents of the stomach leak into the esophagus, in many cases ...

Matrix effects break the LC behavior rule for analytes in LC-MS/MS analysis of biological samples.

Exp. Biol. Med. (Maywood.) 240(4) , 488-97, (2015)

High-performance liquid chromatography (HPLC) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) are generally accepted as the preferred techniques for detecting and quantitating analytes of interest in biological matrices on the basis of the rule ...

Growth, sporulation and enterotoxin production by Clostridium perfringens type A in the presence of human bile salts.

FEMS Microbiol. Lett. 68 , 15-21, (1991)

The effect of human bile juice and bile salts (sodium cholate, sodium taurocholate, sodium glycochenodeoxycholate and sodium chenodeoxycholate) on growth, sporulation and enterotoxin production by enterotoxin-positive and enterotoxin-negative strains of Clost...

Repair of DNA damage induced by bile salts in Salmonella enterica.

Genetics 174 , 575-84, (2006)

Exposure of Salmonella enterica to sodium cholate, sodium deoxycholate, sodium chenodeoxycholate, sodium glycocholate, sodium taurocholate, or sodium glycochenodeoxycholate induces the SOS response, indicating that the DNA-damaging activity of bile resides in...