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16564-43-5

16564-43-5 structure
16564-43-5 structure
  • Name: Glycochenodeoxycholic acid sodium
  • Chemical Name: Glycochenodeoxycholic acid sodium
  • CAS Number: 16564-43-5
  • Molecular Formula: C26H42NNaO5
  • Molecular Weight: 471.605
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2018-03-31 08:00:00
  • Modify Date: 2024-01-05 12:16:41
  • Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].

Name Glycochenodeoxycholic acid sodium
Synonyms Sodium glycochenodeoxycholate
3α,7α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide sodium salt
Sodium {[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]amino}acetate
Glycine, N-((3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl)-, monosodium salt
N-(3α,7α-Dihydroxy-24-oxocholan-24-yl)glycine sodium salt
Glycine, N-[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1)
Glycochenodeoxycholic acid sodium salt
Description Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].
Related Catalog
References

[1]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30.

[2]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

Boiling Point 655.6ºC at 760mmHg
Molecular Formula C26H42NNaO5
Molecular Weight 471.605
Flash Point 350.3ºC
Exact Mass 471.296082
PSA 109.69000
LogP 2.65030
Vapour Pressure 5.74E-20mmHg at 25°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3.0
HS Code 2924299090
Precursor  2

DownStream  2

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%