Glycochenodeoxycholic acid sodium

Modify Date: 2024-01-05 12:16:41

Glycochenodeoxycholic acid sodium Structure
Glycochenodeoxycholic acid sodium structure
Common Name Glycochenodeoxycholic acid sodium
CAS Number 16564-43-5 Molecular Weight 471.605
Density N/A Boiling Point 655.6ºC at 760mmHg
Molecular Formula C26H42NNaO5 Melting Point N/A
MSDS Chinese USA Flash Point 350.3ºC

 Use of Glycochenodeoxycholic acid sodium


Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].

 Names

Name Glycochenodeoxycholic acid sodium
Synonym More Synonyms

 Glycochenodeoxycholic acid sodium Biological Activity

Description Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].
Related Catalog
References

[1]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30.

[2]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

 Chemical & Physical Properties

Boiling Point 655.6ºC at 760mmHg
Molecular Formula C26H42NNaO5
Molecular Weight 471.605
Flash Point 350.3ºC
Exact Mass 471.296082
PSA 109.69000
LogP 2.65030
Vapour Pressure 5.74E-20mmHg at 25°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3.0
HS Code 2924299090

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

Sodium glycochenodeoxycholate
3α,7α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide sodium salt
Sodium {[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]amino}acetate
Glycine, N-((3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl)-, monosodium salt
N-(3α,7α-Dihydroxy-24-oxocholan-24-yl)glycine sodium salt
Glycine, N-[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1)
Glycochenodeoxycholic acid sodium salt