黄肉楠碱结构式
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常用名 | 黄肉楠碱 | 英文名 | Actein |
|---|---|---|---|---|
| CAS号 | 18642-44-9 | 分子量 | 676.834 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C37H56O11 | 熔点 | 246-250ºC | |
| MSDS | N/A | 闪点 | N/A |
黄肉楠碱用途Actein 是从 Cimicifuga foetida 的根茎中分离的三萜糖苷。Actein 通过促进 ROS/JNK 活化和钝化人膀胱癌中的 AKT 途径来抑制细胞增殖,诱导自噬和凋亡。Actein 在体内几乎没有毒性。 |
| 中文名 | 黄肉楠碱 |
|---|---|
| 英文名 | Actein |
| 英文别名 | 更多 |
| 描述 | Actein 是从 Cimicifuga foetida 的根茎中分离的三萜糖苷。Actein 通过促进 ROS/JNK 活化和钝化人膀胱癌中的 AKT 途径来抑制细胞增殖,诱导自噬和凋亡。Actein 在体内几乎没有毒性。 |
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| 相关类别 | |
| 参考文献 |
| 密度 | 1.4±0.1 g/cm3 |
|---|---|
| 熔点 | 246-250ºC |
| 分子式 | C37H56O11 |
| 分子量 | 676.834 |
| 精确质量 | 676.382263 |
| PSA | 156.67000 |
| LogP | 5.67 |
| 外观性状 | 棕色粉末 |
| 折射率 | 1.610 |
| 储存条件 | 2-8℃，干燥，密闭 |
| 危害码 (欧洲) | Xi |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
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Bioactivity-guided isolation of GABA(A) receptor modulating constituents from the rhizomes of Actaea racemosa.
J. Nat. Prod. 73(12) , 2024-8, (2010) Black cohosh (Actaea racemosa) is a frequently used herbal remedy for the treatment of mild climacteric symptoms. In the present study, the modulation of γ-aminobutryic acid (GABA)-induced chloride cu... |
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Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells.
Phytomedicine 15(6-7) , 504-11, (2008) The purpose of this report is to explore the growth inhibitory effect of extracts and compounds from black cohosh and related Cimicifuga species on human breast cancer cells and to determine the natur... |
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Studies on the Chinese crude drug "shoma." IX. Three novel cyclolanostanol xylosides, cimicifugosides H-1, H-2 and H-5, from cimicifuga rhizome.
Chem. Pharm. Bull. 43(5) , 771-6, (1995) Three new cyclolanostanol xylosides were isolated from a batch of commercial Cimicifuga Rhizome, cimicifugoside H-1 (1), C35H52O9, mp 260-262 degrees C, [alpha]D -43.5 degrees, cimicifugoside H-2 (2),... |
| β-D-Xylopyranoside, (1'R,2S,4'S,4aR,5'S,5aR,7R,7aR,7bR,8R,10R,11aS,12aS,12bS,14aR)-7-(acetyloxy)hexadecahydro-4'-hydroxy-1,1,5',7a,8,12a-hexamethylspiro[5H-cyclopropa[1',8'a]naphth[2',1':4,5]indeno [2,1-b]pyran-10(2H),2'-[3,6]dioxabicyclo[3.1.0]hexan]-2-yl |
| (1'R,2S,4'S,4aR,5'S,5aR,7R,7aR,7bR,8R,10R,11aS,12aS,12bS,14aR)-4'-Hydroxy-1,1,5',7a,8,12a-hexamethyl-2-(β-D-xylopyranosyloxy)hexadecahydro-2H-spiro[cyclopropa[1',8a']naphtho[2',1':4,5]indeno[2,1-b] pyran-10,2'-[3,6]dioxabicyclo[3.1.0]hexan]-7-yl acetate |
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