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6,9-二氯-2-甲氧基吖啶

6,9-二氯-2-甲氧基吖啶结构式
6,9-二氯-2-甲氧基吖啶结构式
品牌特惠专场
常用名 6,9-二氯-2-甲氧基吖啶 英文名 6,9-Dichloro-2-methoxyacridine
CAS号 86-38-4 分子量 278.13300
密度 1.399 g/cm3 沸点 444.3ºC at 760 mmHg
分子式 C14H9Cl2NO 熔点 163-165 °C(lit.)
MSDS 中文版 美版 闪点 222.5ºC
符号 GHS07 GHS08
GHS07, GHS08
信号词 Danger

N-cinnamoylation of antimalarial classics: quinacrine analogues with decreased toxicity and dual-stage activity.

ChemMedChem 9(2) , 305-10, (2014)

Plasmodium falciparum, the causative agent of the most lethal form of malaria, is becoming increasingly resistant to most available drugs. A convenient approach to combat parasite resistance is the development of analogues of classical antimalarial agents, ap...

Antimalarial acridines: Synthesis, in vitro activity againstP. falciparumand interaction with hematin

Bioorg. Med. Chem. 17(23) , 8032-9, (2009)

Synthesis of new 9-aminoacridines and evaluation of in vitro anti-malarial activity. Inhibitory effect on haem crystallization.

[Preparation and antileukemic activity of quinolizidinylalkyl-derivatives of 4-aminoquinoline and 9-aminoacridine].

Boll. Chim. Farm. 128(6) , 212-5, (1989)

By reacting three quinolizidinylalkylamines with 4,7-dichloroquinoline and 6,9-dichloro-2-methoxyacridine six derivatives of 4-aminoquinoline and 9-aminoacridine were obtained. These compounds, which are of interest as potential antibacterial, antiprotozoaria...

Origin of the complex fluorescence emission of 9-amino-6-chloro-2-methoxyacridine. 1. Experiment. Fan P, et al.

J. Phys. Chem. 93(18) , 6615-22, (1989)