6,9-Dichloro-2-methoxyacridine

6,9-Dichloro-2-methoxyacridine Structure
6,9-Dichloro-2-methoxyacridine structure
Common Name 6,9-Dichloro-2-methoxyacridine
CAS Number 86-38-4 Molecular Weight 278.13300
Density 1.399 g/cm3 Boiling Point 444.3ºC at 760 mmHg
Molecular Formula C14H9Cl2NO Melting Point 163-165 °C(lit.)
MSDS Chinese USA Flash Point 222.5ºC
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

N-cinnamoylation of antimalarial classics: quinacrine analogues with decreased toxicity and dual-stage activity.

ChemMedChem 9(2) , 305-10, (2014)

Plasmodium falciparum, the causative agent of the most lethal form of malaria, is becoming increasingly resistant to most available drugs. A convenient approach to combat parasite resistance is the development of analogues of classical antimalarial agents, ap...

Antimalarial acridines: Synthesis, in vitro activity againstP. falciparumand interaction with hematin

Bioorg. Med. Chem. 17(23) , 8032-9, (2009)

Synthesis of new 9-aminoacridines and evaluation of in vitro anti-malarial activity. Inhibitory effect on haem crystallization.

[Preparation and antileukemic activity of quinolizidinylalkyl-derivatives of 4-aminoquinoline and 9-aminoacridine].

Boll. Chim. Farm. 128(6) , 212-5, (1989)

By reacting three quinolizidinylalkylamines with 4,7-dichloroquinoline and 6,9-dichloro-2-methoxyacridine six derivatives of 4-aminoquinoline and 9-aminoacridine were obtained. These compounds, which are of interest as potential antibacterial, antiprotozoaria...

Origin of the complex fluorescence emission of 9-amino-6-chloro-2-methoxyacridine. 1. Experiment. Fan P, et al.

J. Phys. Chem. 93(18) , 6615-22, (1989)