雷尼替丁-S-氧化物
雷尼替丁-S-氧化物结构式
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常用名 | 雷尼替丁-S-氧化物 | 英文名 | Ranitidine S-Oxide |
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| CAS号 | 73851-70-4 | 分子量 | 330.40300 | |
| 密度 | 1.265g/cm3 | 沸点 | 527.5ºC at 760 mmHg | |
| 分子式 | C13H22N4O4S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 272.8ºC | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
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Phenotypes of flavin-containing monooxygenase activity determined by ranitidine N-oxidation are positively correlated with genotypes of linked FM03 gene mutations in a Korean population.
Pharmacogenetics 10(1) , 67-78, (2000) A non-invasive urine analysis method to determine the in-vivo flavin-containing mono-oxygenase (FMO) activity catalysing N-oxidation of ranitidine (RA) was developed and used to phenotype a Korean population. FMO activity was assessed by the molar concentrati... |
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Qualitative and quantitative analysis of ranitidine and its metabolites by high-performance liquid chromatography-mass spectrometry.
J. Chromatogr. A. 323(1) , 143-52, (1985) Reversed-phase high-performance liquid chromatography systems for the separation of ranitidine and its metabolites ranitidine-N-oxide, ranitidine-S-oxide, and desmethylranitidine have been developed for use in high-performance liquid chromatography-mass spect... |
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Sulphoxidation and sulphation capacity in patients with primary biliary cirrhosis.
J. Hepatol. 22(5) , 551-60, (1995) We have previously reported an association of impaired S-oxidation with primary biliary cirrhosis. In order to confirm and further define this relationship, we retested S-oxidation capacity via three metabolic pathways and sulphation capacity via a fourth pat... |
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Use of post-column fluorescence derivatization to develop a liquid chromatographic assay for ranitidine and its metabolites in biological fluids.
J. Chromatogr. B. Biomed. Sci. Appl. 693(2) , 443-9, (1997) Ranitidine and its main metabolites, ranitidine N-oxide and ranitidine S-oxide, were determined in plasma and urine after separation using reversed-phase liquid chromatography. The mobile phase consisted of an initial isocratic step with 7:93 (v/v) acetonitri... |