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氯乙酸钠

一般危化品
氯乙酸钠结构式
氯乙酸钠结构式
常用名 氯乙酸钠 英文名 Sodium chloroacetate
CAS号 3926-62-3 分子量 116.479
密度 1.399g/cm3 沸点 189ºC at 760 mmHg
分子式 C2H2ClNaO2 熔点 199 °C (dec.)(lit.)
MSDS 中文版 美版 闪点 270°C
符号 GHS06 GHS09
GHS06, GHS09
信号词 Danger

Mammalian cell cytotoxicity and genotoxicity of the haloacetic acids, a major class of drinking water disinfection by-products.

Environ. Mol. Mutagen. 51(8-9) , 871-8, (2010)

The haloacetic acids (HAAs) are disinfection by-products (DBPs) that are formed during the disinfection of drinking water, wastewaters and recreational pool waters. Currently, five HAAs [bromoacetic acid (BAA), dibromoacetic acid (DBAA), chloroacetic acid (CA...

Chloroacetic acid triggers apoptosis in neuronal cells via a reactive oxygen species-induced endoplasmic reticulum stress signaling pathway.

Chem. Biol. Interact. 225 , 1-12, (2015)

Chloroacetic acid (CA), a chlorinated analog of acetic acid and an environmental toxin that is more toxic than acetic, dichloroacetic, or trichloroacetic acids, is widely used in chemical industries. Furthermore, CA has been found to be the major disinfection...

Ultrasensitive electrochemical immunoassay for avian influenza subtype H5 using nanocomposite.

PLoS ONE 9(4) , e94685, (2014)

We report a novel electrochemical immunosensor that can sensitively detect avian influenza virus H5 subtype (AIV H5) captured by graphene oxide-H5-polychonal antibodies-bovine serum albumin (GO-PAb-BSA) nanocomposite. The graphene oxide (GO) carried H5-polych...

Synthesis and evaluation of the structural and physicochemical properties of carboxymethyl pregelatinized starch as a pharmaceutical excipient.

Saudi Pharm. J. 23 , 698-711, (2015)

A pregelatinized starch (PGS) was derivatized with sodium chloroacetate (SCA) in alcoholic medium under alkaline condition to produce carboxymethyl pregelatinized starch (CMPGS) with various degrees of substitution (DS). Influence of the molar ratio of SCA to...

Lipases as catalysts in synthesis of fine chemicals.

Methods Mol. Biol. 861 , 445-56, (2012)

The application of lipases as catalysts in the synthesis of an intermediate of alfuzosin and lapyrium chloride is described. In the first case, the one-pot procedure to obtain the intermediate involves the treatment of tetrahydrofuroic acid with ethanol in th...

Ethylenediammonium dication: H-bonded complexes with terephthalate, chloroacetate, phosphite, selenite and sulfamate anions. Detailed vibrational spectroscopic and theoretical studies of ethylenediammonium terephthalate.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 99 , 223-33, (2012)

Crystalline complexes between ethylenediammonium dication and terephthalate, chloroacetate, phosphite, selenite and sulfamate anions were obtained by slow evaporation from water solution method. Room temperature powder infrared and Raman measurements were car...

Comparative electrochemical treatments of two chlorinated aliphatic hydrocarbons. Time course of the main reaction by-products.

J. Hazard. Mater. 192(3) , 1555-64, (2011)

Acidic aqueous solutions of the chlorinated aliphatic hydrocarbons 1,2-dichloroethane (DCA) and 1,1,2,2-tetrachloroethane (TCA) have been treated by the electro-Fenton (EF) process. Bulk electrolyses were performed at constant current using a BDD anode and an...

Genotoxicity testing of three monohaloacetic acids in TK6 cells using the cytokinesis-block micronucleus assay.

Mutagenesis 25(5) , 505-9, (2010)

Chemical disinfection of water generates harmful chemical compounds, known as disinfection by-products (DBPs). One class of DBPs is constituted by haloacetic acids (HAAs), the second major group in prevalence (after trihalomethanes) detected in finished drink...

Carboxymethyl Chinese yam starch: synthesis, characterization, and influence of reaction parameters.

Carbohydr. Res. 344(13) , 1764-9, (2009)

Carboxymethyl starch (CMS) was obtained as a product of the reaction of starch and monochloroacetic acid (MCA) in the presence of sodium hydroxide. The influence of the molar ratio of NaOH/AGU, the molar ratio of MCA/AGU, the reaction time, reaction temperatu...

CE-ESI-MS analysis of singly charged inorganic and organic anions using a dicationic reagent as a complexing agent.

Electrophoresis 30(22) , 3918-25, (2009)

A dicationic ion-pairing reagent, N,N'-dibutyl 1,1'-pentylenedipyrrolidinium, was used to form complexes with singly charged anions for their subsequent analysis by CE-ESI-MS in positive ion mode. This methodology offers the advantages of greater versatility ...