N,O-双(三甲基硅基)乙酰胺
N,O-双(三甲基硅基)乙酰胺结构式
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常用名 | N,O-双(三甲基硅基)乙酰胺 | 英文名 | N,O-Bis(trimethylsilyl)acetamide |
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| CAS号 | 10416-59-8 | 分子量 | 203.429 | |
| 密度 | 0.8±0.1 g/cm3 | 沸点 | 162.1±0.0 °C at 760 mmHg | |
| 分子式 | C8H21NOSi2 | 熔点 | 24 °C | |
| MSDS | 中文版 美版 | 闪点 | 65.5±22.6 °C | |
| 符号 |
GHS02, GHS05, GHS07 |
信号词 | Danger |
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A flipped ion pair at the dynein-microtubule interface is critical for dynein motility and ATPase activation.
J. Cell Biol. 208(2) , 211-22, (2015) Dynein is a motor protein that moves on microtubules (MTs) using the energy of adenosine triphosphate (ATP) hydrolysis. To understand its motility mechanism, it is crucial to know how the signal of MT binding is transmitted to the ATPase domain to enhance ATP... |
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Thermostable ricin vaccine protects rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection.
Proc. Natl. Acad. Sci. U. S. A. 112(12) , 3782-7, (2015) Ricin toxin (RT) is the second most lethal toxin known; it has been designated by the CDC as a select agent. RT is made by the castor bean plant; an estimated 50,000 tons of RT are produced annually as a by-product of castor oil. RT has two subunits, a riboto... |
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Identification of protein tyrosine phosphatase receptor gamma extracellular domain (sPTPRG) as a natural soluble protein in plasma.
PLoS ONE 10(3) , e0119110, (2015) PTPRG is a widely expressed protein tyrosine phosphatase present in various isoforms. Peptides from its extracellular domain have been detected in plasma by proteomic techniques. We aim at characterizing the plasmatic PTPRG (sPTPRG) form and to identify its s... |
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Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors.
J. Immunol. 194(7) , 3463-74, (2015) Mesenchymal stromal cells (MSCs) are inherently tumor homing and can be isolated, expanded, and transduced, making them viable candidates for cell therapy. This tumor tropism has been used to deliver anticancer therapies to various tumor models. In this study... |
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Multiplexed microfluidic enzyme assays for simultaneous detection of lipolysis products from adipocytes.
Anal. Bioanal. Chem 406(20) , 4851-9, (2014) Microfluidics has enabled new cell biology experiments. Incorporating chemical monitoring of cellular secretion into chips offers the potential to increase information content and utility of such systems. In this work, an integrated, multilayer polydimethylsi... |
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Direct silylation of Trypanosoma brucei metabolites in aqueous samples and their GC-MS/MS analysis.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 134-8, (2014) A simple two-step method for the derivatization of polar compounds (lactate, alanine, glycerol, succinate and glucose) using hexamethyldisilazane (HMDS) and N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) was developed. This method allows direct derivatizat... |
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DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance.
Oncotarget 6(4) , 2134-47, (2015) Though metastatic cancers often initially respond to genotoxic therapeutics, acquired resistance is common. In addition to cytotoxic effects on tumor cells, DNA damaging agents such as ionizing radiation and chemotherapy induce injury in benign cells of the t... |
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Quantification of Sorafenib in Human Serum by Competitive Enzyme-Linked Immunosorbent Assay.
Biol. Pharm. Bull. 38 , 1788-93, (2015) The multikinase inhibitor sorafenib has been used in the treatment of hepatocellular carcinoma, renal cell carcinoma, and differentiated thyroid carcinoma. Here we have demonstrated the production of the first specific antibody against sorafenib. Anti-sorafen... |
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Targeted Delivery of 5-fluorouracil with Monoclonal Antibody Modified Bovine Serum Albumin Nanoparticles.
Iran. J. Pharm. Res. 14(2) , 395-405, (2015) Herein, 1F2, an anti-HER2 monoclonal antibody (mAb), was covalently coupled to the surface of 5-Fluorouracil (5-FU) loaded bovine serum albumin (BSA) nanoparticles. Concerning two different crosslinkers for conjugation of 1F2, Maleimide-poly (ethylene glycol)... |
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Diagnostic performance study of an antigen microarray for the detection of antiphospholipid antibodies in human serum.
Clin. Chem. Lab Med. 53(5) , 801-8, (2015) The parallelization of clinically relevant antigens in a microarray format is of growing importance due to the ability to measure multiple antigen-antibody interactions. With the development of a microarray for the detection of antiphospholipid antibodies we ... |