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3-氨基-5-羟基吡唑

3-氨基-5-羟基吡唑结构式
3-氨基-5-羟基吡唑结构式
品牌特惠专场
常用名 3-氨基-5-羟基吡唑 英文名 3-Amino-5-pyrazolone
CAS号 6126-22-3 分子量 99.091
密度 1.6±0.1 g/cm3 沸点 479.5±25.0 °C at 760 mmHg
分子式 C3H5N3O 熔点 214 °C (dec.)(lit.)
MSDS 中文版 美版 闪点 243.8±23.2 °C
符号 GHS07
GHS07
信号词 Warning

Synthesis of 2,6-difluoro-N-(3-[11C]methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide as a new potential PET agent for imaging of B-Raf(V600E) in cancers.

Bioorg. Med. Chem. Lett. 23(4) , 1017-21, (2013)

The authentic standard 2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide was synthesized from 2,6-difluorobenzoic acid and 3-amino-5-hydroxypyrazole in 9 steps with 1% overall chemical yield. Direct desmethylation of t...

One-step synthesis of diarylpyrazolo[3,4-b]pyridines from isoflavones.

J. Comb. Chem. 12(4) , 600-3, (2010)

A new concise, facile, and efficient method for the synthesis of 3-hydroxy-5,6-diphenylpyrazolo[3,4-b]pyridine derivatives has been described. The cyclocondensation of isoflavones with 3-amino-5-hydroxypyrazole in the presence of sodium methoxide gave fused h...

Molecular structure and vibrational spectra of 3-amino-5-hydroxypyrazole by density functional method.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 71(5) , 1776-82, (2009)

In this work, we report a combined experimental and theoretical study on molecular and vibrational structure of 3-amino-5-hydroxypyrazole (3A5HP). The Fourier transform infrared and Fourier transform Raman spectra of 3A5HP were recorded in the solid phase. Th...