(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐
(2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐结构式
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常用名 | (2S,3R)-3-氨基-2-羟基-4-苯基丁酸盐酸盐 | 英文名 | (2s,3r)-3-amino-2-hydroxy-4-phenylbutyric acid hydrochloride |
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| CAS号 | 128223-55-2 | 分子量 | 231.67600 | |
| 密度 | N/A | 沸点 | 428.5ºC at 760mmHg | |
| 分子式 | C10H14ClNO3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 213ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Bestatin analogue from Streptomyces neyagawaensis SL-387.
Biosci. Biotechnol. Biochem. 60 , 898-900, (1996) A bestatin analogue, (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl-L-valine (AHPA-Val), from the culture filtrate of Streptomyces neyagawaensis SL-387 was obtained in a chemically defined medium containing DL-3-amino-3-phenylpropionic acid. AHPA-Val was 6 times ... |
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2S,3R 3-amino-2-hydroxy-4-phenylbutanoic acid derivatives, enkephalinase inhibitors, augment met5-enkephalin-induced antinociception.
Jpn. J. Pharmacol. 46 , 205-210, (1988) It has been accepted that the periaqueductal gray matter of the mid brain (PAG) and the reticular formation of the medulla oblongata in the brain stem have antinociceptive roles in the pain control pathways of mammals, and met5-enkephalin may act as one of th... |
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Relationship between enhancement of morphine analgesia and inhibition of enkephalinase by 2S, 3R 3-amino-2-hydroxy-4-phenylbutanoic acid derivatives.
Life Sci. 30 , 1739-1746, (1982) The effects of nineteen AHPA* derivatives were examined on morphine analgesia by tail-flick test in rats and on enkephalinase inhibition which was based on the formation of tyrosyl-glycyl-glycine from met-enkephalin. The correlation between the enhancement of... |
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Biological activity of the main metabolites of ubenimex in humans.
J. Antibiot. 41 , 1862-1867, (1988) The biological activity of the two main metabolites of ubenimex in humans, (-)-N-[(2S,3R)-3-amino-2-hydroxy-4-(4'-hydroxy)phenylbutyryl]-L-leucine (OH-ubenimex) and (2S,3R)-3-amino-2-hydroxy-4-phenylbutyric acid [2S,3R)-AHPA) was examined. OH-Ubenimex was alm... |