FTY720(S)-磷酸盐
FTY720(S)-磷酸盐结构式
|
常用名 | FTY720(S)-磷酸盐 | 英文名 | (S) FTY720 Phosphate |
|---|---|---|---|---|
| CAS号 | 402616-26-6 | 分子量 | 387.451 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 584.2±60.0 °C at 760 mmHg | |
| 分子式 | C19H34NO5P | 熔点 | 184-186ºC | |
| MSDS | 美版 | 闪点 | 307.1±32.9 °C |
|
Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory.
Nat. Neurosci. 17(7) , 971-80, (2014) FTY720 (fingolimod), an FDA-approved drug for treatment of multiple sclerosis, has beneficial effects in the CNS that are not yet well understood, independent of its effects on immune cell trafficking. We show that FTY720 enters the nucleus, where it is phosp... |
期刊文献综述：
更多...